Results 211 to 220 of about 988,166 (377)

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

open access: yesAdvanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi   +11 more
wiley   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo   +10 more
wiley   +1 more source

Pericyte‐Assisted Vascular Lumen Organization in a Novel Dynamic Human Blood‐Brain Barrier‐on‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Organ‐on‐Chip (OoC) technology enables the precise modeling of the blood‐brain barrier (BBB). This study presents a microfluidic device that mimics brain microvessels, integrating co‐culture with pericytes and astrocytes under pulsatile flow. Results show that perivascular cells modulate endothelial morphology, promoting lumen formation and barrier ...
Vita Guarino   +9 more
wiley   +1 more source

Graded Hydroxyapatite Triply Periodic Minimal Surface Structures for Bone Tissue Engineering Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the role of triply periodic minimal structures in load bearing bone tissue engineering applications. Research uses a combination of mechanical testing, material characterization, and in vitro tests to study the impact of TPMS lattice structures (gyroid, lidinoid and split‐P).
Tejas M. Koushik   +2 more
wiley   +1 more source

Limited cell-autonomous anticancer mechanisms in long-lived bats. [PDF]

open access: yesNat Commun
Athar F   +14 more
europepmc   +1 more source

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