Results 191 to 200 of about 554,180 (264)

Thiolated Polymers in 3D Bioprinting: Control of Gelation

Advanced Materials, EarlyView.
Thiolated polymers are established as programmable bioinks for 3D bioprinting, integrating versatile crosslinking chemistries with redox‐responsive control. This work demonstrates how molecular design and external triggers define gelation kinetics, printability windows, and structural fidelity, enabling stable, high‐resolution constructs and advancing ...
Soheil Haddadzadegan, Flavia Laffleur, Andreas Bernkop‐Schnürch   +2 more
wiley   +1 more source

TGFb signaling instructs a conserved fibrosis-associated cell state marked by LRRC15. [PDF]

Proc Natl Acad Sci U S A
Shyer JA, Wehbe F, Davidson CD, Bender HS, Thai M, Cox C, Missarova A, Arlantico A, Hall B, Zhang R, Kim D, Altieri A, Hasan S, Namdar A, Chen T, Hakim SW, Guidos C, Brightbill HD, Kuo T, Heimberg G, Corrada Bravo H, Ratsimandresy RA, Uttarwar S, Teng G, Salem O, Arjomandi M, Wilson MS, Darmanis S, Ziai J, Scherl A, Modrusan Z, Wolters PJ, Buechler MB, Vander Heiden JA, Turley SJ.   +34 more
europepmc   +1 more source

Engineering Strain‐Stiffening Granular Hydrogels for 3D‐Printed Tissue‐Mimicry

Advanced Materials, EarlyView.
A 3D‐printable strain‐stiffening double‐network granular hydrogel (SDGH) enables independent, region‐specific tuning of toe (EToe) and heel (EHeel) moduli through control of microgel packing and network composition. This platform replicates tissue‐like nonlinear mechanics and allows fabrication of high‐fidelity, multilayered aortic valves with ...
Hyeokju Chae, Joohwan Han, Jeong‐Wook Seo, Taehoon Lee, Kihyeon Bae, Yeontaek Lee, Dong Soo Kim, Ikjin Kim, Jin‐Oh Kim, Steve Park   +9 more
wiley   +1 more source

Co-Culture of nasopharyngeal carcinoma cells and fibroblasts induces altered integrin expression associated with 3D structural formation. [PDF]

Cytotechnology
Liang J, Zhu M, Peng X, Pan S, Peng Z, Tang M.   +5 more
europepmc   +1 more source

Soft, Degradable, and Magnetic Microcarriers for Encapsulation and Guided Transport of Drugs and 3D Spheroids

Advanced Materials, EarlyView.
This work presents soft, degradable hydrogel microcarriers that combine magnetic responsiveness with the ability to host multiple therapeutic and cellular components. Produced by droplet microfluidics, the carriers maintain structural integrity during manipulation, permit controlled breakdown under physiological conditions, and enable guided motion for
Xuan Peng, Lulu Song, Daryna Mruga, Veronika Bakhmat, Sergei Dzyadevych, Lin Guo, Shahrukh Shakeel, Rico Illing, Olha Bezsmertna, Xiaotao Wang, Nicholas R. Posselli, Sarthak Misra, Sandra Hauser, Jens Pietzsch, Klaus Kopka, Denys Makarov, Željko Janićijević, Xinne Zhao, Larysa Baraban   +18 more
wiley   +1 more source

Macropinocytosis inhibition attenuates profibrotic responses in lung fibroblasts and pulmonary fibrosis models. [PDF]

J Clin Invest
Rosas IO, McDowell-Sanchez AK, Sanchez S, Cala-Garcia JD, Waich Cohen AR, Ruiz-Echartea E, Ochsner SA, Kraushaar DC, Celada LJ, Sun D, Polverino F, Coarfa C, McKenna NJ, Tsoyi K.   +13 more
europepmc   +1 more source

Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues

Advanced Materials Interfaces, EarlyView.
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike, Dhananjay V. Deshmukh, Mark W. Tibbitt, Céline Labouesse   +3 more
wiley   +1 more source

Diminished and Altered Cellular Senescence Response in Delayed Wound Healing of Aging. [PDF]

Aging Cell
Shvedova M, Thanapaul RJRS, Wang Q, Shin GH, Dhillon J, Roh DS.   +5 more
europepmc   +1 more source

Multilayered Digital Microfluidic Chip for Cell‐Based Assays

Advanced Materials Interfaces, EarlyView.
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden, Oksana K. Savchak, Burcu Gumuscu   +2 more
wiley   +1 more source

From inflammation to malignancy: the dynamic evolution of cancer-associated fibroblasts in IBD-CRC. [PDF]

Neoplasia
Naito N, Kasashima H, Fukuoka T, Nakanishi Y, Ohtani N, Maeda K.   +5 more
europepmc   +1 more source