We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim +7 more
wiley +1 more source
IL1β<sup>+</sup> macrophages promote intestinal fibrosis in Crohn's disease by secreting AREG to activate PI16<sup>+</sup> fibroblasts. [PDF]
Xie H +19 more
europepmc +1 more source
Biocompatible but Antibacterial Mechanism of Graphene Oxide for Sustainable Antibiotics
Graphene oxide (GO) exhibits selective antibacterial activity through specific interactions between its oxygen functional groups and bacterial membrane phospholipid POPG, causing membrane destabilization while maintaining biocompatibility. Model membrane studies and infected wound models in mice and pigs demonstrate effective bacterial suppression and ...
Sujin Cha +15 more
wiley +1 more source
Sea Cucumber Collagen Peptides Exert an Anti-Skin Aging Effect by Inhibiting Endoplasmic Reticulum Stress in Fibroblasts. [PDF]
Mi R +7 more
europepmc +1 more source
The conductive and stretchable photothermal CuSe fiber is fabricated for versatile biomedical applications. This CuSe fiber functions as a reliable wearable strain sensor and heater due to its high conductivity, stretchability and photothermal efficiency.
Kukro Yoon +9 more
wiley +1 more source
Milk fat globule EGF and factor V/VIII domain containing (MFGE8) as a novel player in equine endometrial fibrosis. [PDF]
Zu Klampen E, Neufeld G, Klein C.
europepmc +1 more source
Assembly of Cell‐Seeded 3D Printed Hydrogel Modules with Perfusable Channel Networks
Macroscale assembly was utilized to prepare perfusable tissue constructs from individually 3D printed hydrogel modules with embedded branched channel networks and port arrays for cell seeding. Novel multi‐material bioreactors were fabricated to facilitate the gluing of individual modules and the perfusion culture of assembled modular constructs seeded ...
Zachary J. Geffert +10 more
wiley +1 more source
Fibroblast growth factor-inducible 14 accelerates pulmonary fibrosis by inducing fibroblast senescence in mice. [PDF]
Guan XX +11 more
europepmc +1 more source
Active Learning‐Accelerated Discovery of Fibrous Hydrogels with Tissue‐Mimetic Viscoelasticity
Active learning accelerates the design of fibrous hydrogels that mimic the viscoelasticity of native tissues. By integrating multi‐objective optimization and closed‐loop experimentation, this approach efficiently identifies optimal formulations from thousands of possibilities and decouples elasticity and viscosity. The resulting hydrogels offer tunable
Zhengkun Chen +11 more
wiley +1 more source
Impact of acute blue light irradiation on the molecular clock and markers associated with photoaging in skin cell models. [PDF]
Vibriani A +3 more
europepmc +1 more source

