Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi+13 more
wiley +1 more source
Using chanarin-dorfman syndrome patient fibroblasts to explore disease mechanisms and new treatment avenues. [PDF]
Angel M+13 more
europepmc +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source
Elevated CD47 Expression Impairs Elimination of Photoaged Fibroblasts by Macrophages and Serves as a Potential Biomarker for Photoaging. [PDF]
Xu X, Lu X, Chen X, Yao A, Lai W.
europepmc +1 more source
Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan+8 more
wiley +1 more source
Selective activation of antioxidant resources and energy deficiency in Marinesco-Sjögren syndrome fibroblasts as an adaptive biological response to Sil1 loss. [PDF]
Panella V+5 more
europepmc +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
Mitochondrial and energy metabolism dysfunctions are hallmarks of TDP-43<sup>G376D</sup> fibroblasts from members of an Amyotrophic Lateral Sclerosis family. [PDF]
Perciballi E+22 more
europepmc +1 more source
Demonstration of dual rhinovirus infection in humans by isolation of different serotypes in human heteroploid (HeLa) and human diploid fibroblast cell cultures [PDF]
Marion K. Cooney, G E Kenny
openalex +1 more source
Non‐Surgical, In‐Stent Membrane Bioelectronics for Long‐Term Intracranial Pressure Monitoring
This image shows a sequence of long‐term intracranial pressure monitoring using non‐surgical, in‐stent membrane bioelectronics. Abstract Traditional intracranial pressure (ICP) monitoring methods, using intraventricular catheters, face significant limitations, including high invasiveness, discrete data, calibration complexities, and drift issues, which
Jimin Lee+9 more
wiley +1 more source