Results 31 to 40 of about 3,826 (203)

Fibrodysplasia Ossificans Progressiva

Annals of Saudi Medicine, 1999
Fibrodysplasia ossificans progressiva (FOP) is a rare disorder. The striking features of the disorder are the replacement of muscles, tendons, and aponeuroses by masses of bone, and the presence of certain skeletal abnormalities. In this report, we describe a woman who has literally grown up in bed since the age of three years.
A H, Zargar, B A, Laway, S R, Masoodi, A I, Wani, M I, Bashir, M M, Wani   +5 more
openaire   +2 more sources

Pediatric myositis ossificans circumscripta following traumatic hip dislocation: A case report

Radiology Case Reports, 2023
Myositis ossificans is non-neoplastic heterotopic bone forms in skeletal muscle. We recognize 3 subtypes: fibrodysplasia ossificans progressiva, myositis ossificans with no history of trauma (nontraumatic or pseudomalignant), and circumscribed or ...
Khadija Laasri, MD, Siham El Haddad, PhD, Salma Marrakchi, MD, Ismail Mohamed Halfi, MD, Nazik Allali, PhD, Latifa Chat, PhD   +5 more
doaj   +1 more source

Challenges and Opportunities for Drug Repositioning inFibrodysplasia Ossificans Progressiva [PDF]

, 2021
Fibrodysplasia ossificans progressiva (FOP) is an ultrarare congenital disease that progresses through intermittent episodes of bone formation at ectopic sites.
Bullock, Alex N., Goumans, Marie José, Ikeya, Makoto, Sanchez Duffhues, Gonzalo, Ten Dijke, Peter, Ventura Pujol, Francesc, Williams, Eleanor   +6 more
core   +2 more sources

FIBRODYSPLASIA OSSIFICANS PROGRESSIVA

British Journal of Anaesthesia, 1990
A 14-yr-old boy with fibrodysplasia ossificans progressiva (FOP) presented for surgery for bilateral division of his ossified masseter muscles. Patients with FOP may present problems to the anaesthetist, including difficulties with tracheal intubation, restrictive pulmonary disease and abnormalities of cardiac conduction.
M C, Newton, P W, Allen, D C, Ryan
openaire   +2 more sources

A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders

Nature Communications, 2023
Mutations in activin receptor-like kinase 2 (ALK2) can cause the pathological osteogenic signaling seen in some patients with fibrodysplasia ossificans progressiva and other conditions such as diffuse intrinsic pontine glioma.
Takenobu Katagiri, Sho Tsukamoto, Mai Kuratani, Shinnosuke Tsuji, Kensuke Nakamura, Satoshi Ohte, Yoshiro Kawaguchi, Kiyosumi Takaishi   +7 more
doaj   +1 more source

Early Detection for Better Patient Outcome: A Case Report on Two Patients Presenting With Fibrodysplasia Ossificans Progressiva at Tikur Anbessa Specialized Hospital, Ethiopia. [PDF]

Case Rep Orthop
Fibrodysplasia ossificans progressiva is an ultrarare disorder of endochondral ossification. It is unfamiliar to most care providers in low‐income countries such as Ethiopia. Even though the clinical presentation is typical, most cases remain misdiagnosed in our region.
Haile AM, Azale AW, Ayana B.
europepmc   +2 more sources

Nodular osteochondrogenic activity in soft tissue surrounding osteoma in neurogenic para osteo-arthropathy: morphological and immunohistochemical study [PDF]

, 2004
Background Neurogenic Para-Osteo-Arthropathy (NPOA) occurs as a consequence of central nervous system injuries or some systemic conditions. They are characterized by bone formation around the main joints.
T Youssefian, R Sapena, R Carlier, C Bos, A Denormandie, P Denys, A Cormier, M Bandelier, A Chantraine, T Ebinger, A Dejerine, AM Richards, AB Taly, AM Hernandez, P Kjaersgaard-Andersen, EL Bressler, J DeLee, OS Nilsson, AI Caplan, SP Bruder, GS Stein, AI Caplan, MCMBDAHMCIWPRGEMW Cassar-Pullicino VN, JT Campbell, A Horner, Q Chen, AG Nerlich, AB Rossier, P Denormandie, P Denormandie, P Denormandie, A Chantraine, A Chantraine, H Selye, H Selye, K Mizuno, MR Urist, FS Kaplan, FH Gannon, P Gallien, BK Hall, E Schipani, CE Farnum, OTEFDPSDJ Carter DR, CDR Wong M, DE Garland, Z Feldman, MHJ KURER, CT Brighton, Bassett, K Vargervik   +50 more
core   +2 more sources

Current state of therapeutic development for rare cancers in Japan, and proposals for improvement [PDF]

, 2018
This article discusses current obstacles to the rapid development of safe and effective treatments for rare cancers, and considers measures required to overcome these challenges.
Ando Masashi, Goto Toshio, Heike Toshio, Kawai Akira, Kimura Shinya, Matsui Shigeyuki, Matsumoto Seiichi, Mizutani Shuki, Monden Morito, Nagata Kyosuke, Narukawa Mamoru, Nishikawa Akiyoshi, Shibata Taro, Shibata Tatsuhiro, Tani Kenzaburo, Toguchida Junya, Ueda Ryuzo, 永田 恭介   +17 more
core   +2 more sources

When Limb Surgery Has Become the Only Life-Saving Therapy in FOP: A Case Report and Systematic Review of the Literature [PDF]

, 2020
Fibrodysplasia ossificans progressiva (FOP) is a rare disease in which heterotopic ossification (HO) is formed in muscles, tendons and ligaments. Traumatic events, including surgery, are discouraged as this is known to trigger a flare-up with risk of ...
Botman, Esmée, Bravenboer, Nathalie, Coen Netelenbos, J, de Graaf, Pim, de Vries, Ralph, Eekhoff, Elisabeth M W, Grunwald, Zvi, Lubbers, Wouter D, Micha, Dimitra, Nieuwenhuijzen, Jakko A, Peters, Edgar J G, Raijmakers, Pieter G H M, Sabelis, Louise, Schober, Patrick R, Schwarte, Lothar A, Smilde, Bernard J, Smit, Jan Maerten, Teunissen, Bernd P, Treurniet, Sanne, van Schie, Annelies, Visser, Marieke   +20 more
core   +2 more sources

Fibrodysplasia ossificans progressiva: a case report

The Turkish Journal of Pediatrics, 2014
Fibrodysplasia ossificans progressiva (FOP) is a rare, severely disabling, autosomal dominant disease characterized by recurrent painful episodes of soft tissue swelling and the development of heterotopic ossification. The main target is the axial
Merih Önal, M Demir Bajin, Taner Yılmaz   +2 more
doaj   +5 more sources