Results 41 to 50 of about 3,826 (203)

Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage [PDF]

open access: yes, 2009
We report a novel technology for the rapid healing of large osseous and chondral defects, based upon the genetic modification of autologous skeletal muscle and fat grafts.
A Walsh   +15 more
core   +4 more sources

Fibrodysplasia ossificans progressiva: a case report and literature review

open access: yesJournal de la Faculté de Médecine d'Oran, 2020
Introduction Fibrodysplasia Ossificans Progressiva (FOP) is an extremely rare genetic disease characterized by heterotopic ossification of muscles and connective tissue occurring in relapses, which can lead to the creation of a real second skeleton. The
Amina CHENTOUF
doaj   +2 more sources

An extreme entity in differential diagnosis of musculoskeletal involvement-fibrodysplasia ossificans progressiva: a case based review

open access: yesThe Turkish Journal of Pediatrics, 2018
Fibrodysplasia ossificans progressiva is one of the most devastating disorder of mankind characterized by progressive heterotopic ossification. Apart from hallux valgus, other symptoms start to develop in the first decade of life.
Mustafa Çakan   +3 more
doaj   +1 more source

Fibrodysplasia ossificans progressiva in Hong Kong—A case report series

open access: yesFrontiers in Pediatrics, 2023
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare condition. The diagnosis could be challenging due to its rarity and non-specific presenting symptoms.
Joshua Chun Ki Chan   +10 more
doaj   +1 more source

Fibrodyslasia (Myositis) ossificans progressiva- A case report [PDF]

open access: yes, 2016
We are presenting a case report of an 18yr old kenyan girl with big toe/ thumb anomalies and a 3 year history of heterotopic ossification of the temporo-mandibular joints, cervical spine, shoulders, elbows, lumbar spine and abdominal wall.
Mead, TC, Muteti, EN
core   +2 more sources

Insights into the biology of fibrodysplasia ossificans progressiva using patient-derived induced pluripotent stem cells

open access: yesRegenerative Therapy, 2019
The demand for development of new drugs remains on the upward trend because of the large number of patients suffering from intractable diseases for which effective treatment has not been established yet.
Taiki Nakajima, Makoto Ikeya
doaj   +1 more source

New Spontaneous Model of Fibrodysplasia Ossificans Progressiva [PDF]

open access: yes, 2008
We report the first known example of spontaneous, naturally occurring fibrodysplasia ossificans progressiva (FOP) in a mammal. The Southeast Asian mouse deer of the genus _Tragulus_ (Artiodactyla: Tragulidae) have an osseous sheath covering the lower ...
Bruce Rothschild   +2 more
core   +1 more source

Revision Distal Bicep Repair in the Setting of Heterotopic Ossification: Case Study

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
Radiographic and intraoperative findings demonstrating heterotopic ossification following distal biceps tendon repair. ABSTRACT Heterotopic ossification (HO) following distal biceps tendon repair is an uncommon but potential complication. This may present pain, limited range of motion, or sensory changes due to nerve compression.
Aidan M. Brikho   +2 more
wiley   +1 more source

Recent Topics in Fibrodysplasia Ossificans Progressiva [PDF]

open access: yesEndocrinology and Metabolism, 2018
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease that is characterized by the formation of heterotopic bone tissues in soft tissues, such as skeletal muscle, ligament, and tendon.
Takenobu Katagiri   +3 more
doaj   +1 more source

Evaluation of clinical cardiac safety of zilurgisertib, an activin receptor‐like kinase‐2 (ALK2) inhibitor, in healthy participants

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.
Abstract The oral, small molecule inhibitor of activin receptor‐like kinase‐2, zilurgisertib (INCB000928), is under evaluation in fibrodysplasia ossificans progressiva. Cardiac safety was assessed using electrocardiogram (ECG) parameters and a plasma concentration‐heart rate‐corrected QT (C‐QTc) interval analysis of pooled data from single ascending ...
Yan‐ou Yang   +5 more
wiley   +1 more source

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