Results 71 to 80 of about 44,644 (146)

Future of fibrodysplasia ossificans progressiva management: A systematic review of investigational therapies

Rheumatology &Autoimmunity, Volume 5, Issue 1, Page 28-36, March 2025.
Fibrodysplasia ossificans progressiva, a rare genetic disorder caused by ACVR1 mutations, leads to soft tissue ossification. Recent advancements, including food and drug administration‐approved palovarotene, show promise despite safety concerns. Therapies like tofacitinib and imatinib demonstrate potential, but larger, controlled trials are essential ...
Muhammad Ikrama, Muhammad Usama, Shifa Israr, Maryam Humayon, Muhammad Umair Javaid, Shafqat Abbas, Muhammad Aliyan Haider   +6 more
wiley   +1 more source

Influenza-like Viral Illnesses and Flare-ups of Fibrodysplasia Ossificans Progressiva [PDF]

, 2004
Flare-ups of fibrodysplasia ossificans progressiva are most commonly triggered by soft tissue trauma. After observing severe flare-ups of fibrodysplasia ossificans progressiva in two half-sisters with culture-confirmed influenza B infections, we ...
Shore, Eileen, Scarlett, Richard F., Rocke, David, Patel, Jean, Kaplan, Frederick S., Kantanie, Sharon   +5 more
core   +1 more source

Fibrodysplasia Ossificans Progressiva: Clinical and Genetic Aspects

Orphanet Journal of Rare Diseases, 2011
Fibrodysplasia ossificans progressiva (FOP) is a severely disabling heritable disorder of connective tissue characterized by congenital malformations of the great toes and progressive heterotopic ossification that forms qualitatively normal bone in ...
Pignolo Robert J, Shore Eileen M, Kaplan Frederick S   +2 more
doaj   +1 more source

Fibrodysplasia Ossificans Progressiva in an Adult Indian Male

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Following its first description by Guy Patin in 1692 as a disease that turned a woman into wood, Fibrodysplasia Ossificans Progressiva has maintained its low profile that too mainly in textbooks and rarely does one encounter a live walking individual ...
Rachit Harjai, Sushil Ghanshyam Kachewar
doaj  

Fibrodysplasia ossificans progressiva: case report Fibrodisplasia ossificante progressiva: relato de caso

Arquivos de Neuro-Psiquiatria, 2005
Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disorder characterized by postnatal progressive heterotopic ossification of the connective tissue and congenital malformation of the big toes. We report on a nine-year-old girl with
Andre Leite Gonçalves, Marcelo Rodrigues Masruha, Carmelinda Correia de Campos, Patricia Longo Ribeiro Delai, Luiz Celso Pereira Vilanova   +4 more
doaj   +1 more source

Immunologic Aspects in Fibrodysplasia Ossificans Progressiva

Biomolecules
Background: Inflammation is a major driver of heterotopic ossification (HO), a condition of abnormal bone growth in a site that is not normally mineralized.
Anastasia Diolintzi, Mst Shaela Pervin, Edward C. Hsiao   +2 more
doaj   +1 more source

Picture Story A case of fibrodysplasia ossificans progressiva

, 2014
Fibrodysplasia ossificans progressiva (FOP) is a dominantly inherited connective tissue disorder in which defects in skeletal patterning are associated with progressive endochondral ossification of large ...
Sarangapani Arulprakash, Rakesh Kain, Maya Chansoria   +2 more
core  

Picture story A Sri Lankan child with fibrodysplasia ossificans progressiva

, 2014
Fibrodysplasia ossificans progressiva (FOP) is a severe, rare condition of ectopic ossification with primary involvement of the skeletal muscles, associated with characteristic skeletal abnormalities ...
Rohan Aloysius, K G R H Dharmawardane, M S S Fern   +2 more
core  

Fibrodysplasia ossificans progressiva [PDF]

The Indian Journal of Pediatrics, 1994
S, Ganguly, D K, Paul, B, Ghosal, A, Choube   +3 more
openaire   +3 more sources

Mutations in ACVR1 that result in Fibrodysplasia ossificans progressiva

, 2019
Analyzing the various point mutations in the coding of ACVR1 that result in connective tissue disease Fibrodysplasia ossificans progressiva by using various molecular dynamics ...
Weatherby, William
core