Results 111 to 120 of about 354,159 (381)

Efficient Isolation and Enrichment of Mesenchymal Stem Cells from Human Embryonic Stem Cells by Utilizing the Interaction between Integrin α5β1 and Fibronectin

Advanced Science, 2020
Human pluripotent stem cells (hPSCs) are a potent source of clinically relevant mesenchymal stem cells (MSCs) that confer functional and structural benefits in cell therapy and tissue regeneration.
Byung‐Hyun Cha, Jin‐Su Kim, Alvin Bello, Geun‐Hui Lee, Do‐Hyun Kim, Byoung Ju Kim, Yoshie Arai, Bogyu Choi, Hansoo Park, Soo‐Hong Lee   +9 more
doaj   +1 more source

Fibronectin at select sites binds multiple growth factors (GF) and enhances their activity: expansion of the collaborative ECM-GF paradigm

Journal of Investigative Dermatology, 2013
Intensive research has demonstrated that extracellular matrix (ECM) molecules and growth factors (GF) collaborate at many different levels. The ability of ECM to modulate GF signals has important implications in tissue formation and homeostasis as well ...
Jia Zhu, R. Clark
semanticscholar   +1 more source

A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques. [PDF]

, 1992
A point mutation in a highly conserved region of the beta 1 subunit, Asp130 to Ala (D130A) substitution, abrogates the Arg-Gly-Asp (RGD)-dependent binding of alpha 5 beta 1 to fibronectin (FN) without disrupting gross structure or heterodimer assembly ...
Ginsberg, MH, Mandelman, D, Puzon, W, Takada, Y, Ylänne, J   +4 more
core   +2 more sources

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Advanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich   +11 more
wiley   +1 more source

Alterations in proteins of bone marrow extracellular matrix in undernourished mice

Brazilian Journal of Medical and Biological Research, 2000
The objective of the present study was to determine the effect of protein malnutrition on the glycoprotein content of bone marrow extracellular matrix (ECM).
C.L. Vituri, M. Alvarez-Silva, A.G. Trentin, P. Borelli   +3 more
doaj   +1 more source

Changing the mechanical unfolding pathway of FnIII10 by tuning the pulling strength [PDF]

, 2008
We investigate the mechanical unfolding of the tenth type III domain from fibronectin, FnIII10, both at constant force and at constant pulling velocity, by all-atom Monte Carlo simulations.
Abu-Lail, Alberto Imparato, Alessandro Torcini, Anders Irbäck, Aota, Baneyx, Bell, Cota, Craig, Crooks, DeLano, Dudko, Erickson, Evans, Favrin, Ferrenberg, Gao, Geiger, Harris, Hummer, Hyeon, Imparato, Imparato, Imparato, Imparato, Imparato, Imparato, Irbäck, Irbäck, Irbäck, Irbäck, Irbäck, Jarzynski, Kleiner, Klimov, Krammer, Li, Li, Li, Li, Li, Lu, Main, Marko, Ng, Oberhauser, Ohashi, Paci, Plaxco, Ruoslahti, Schlierf, Simon Mitternacht, Smith, Stefano Luccioli, Sułkowska, Vogel, West, West   +57 more
core   +3 more sources

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Advanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley   +7 more
wiley   +1 more source

The Induction of EMT and Activation of Adipose Stem Cells in Correlation with the Secretion of LTBP-1 in Mammary Cells [PDF]

, 2015
This work is part of an ongoing study that investigates the upregulation of LTBP-1 in mammary epithelial cells as well as the differentiation of breast adipose stem cells (BASCs) in the presence of TGF-β1.
Griggs, Lauren, Lemmon, Dr. Christopher, PhD, Malik, Roshni   +2 more
core   +1 more source

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteins.

FEMS Microbiology Reviews, 2011
Fibronectin, a large and essential multidomain glycoprotein, with multiple adhesive properties, functioning as a key link between cells and their extracellular matrices, is now recognized to be the target for a large number of bacterial proteins, which ...
B. Henderson, S. Nair, Jaqueline Pallas, Mark A. Williams   +3 more
semanticscholar   +1 more source