Results 91 to 100 of about 247,327 (296)

Fibronectin-Coated MetalPhenolic Networks for Cooperative Tumor Chemo-/Chemodynamic/Immune Therapy via Enhanced Ferroptosis-Mediated Immunogenic Cell Death

, 2022
The development of nanomedicine formulations to overcome the disadvantages of traditional chemotherapeutic drugs and integrate cooperative theranostic modes still remains challenging.
Liang Jia, Yunqi Guo, Xiangyang Shi (550246), Liang Jia (212225), Mingwu Shen, Mengsi Zhan (10056444), Yunqi Guo (11713858), Shaoli Song, Changchang Zhang, Chunjuan Jiang, Yao Xu (247302), Shaoli Song (412493), Mingwu Shen (550245), Chunjuan Jiang (11808670), Changchang Zhang (4740444), Yao Xu, Mengsi Zhan, Xiangyang Shi   +17 more
core   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source

Ovarian cancer relies on the PDGFRβ–fibronectin axis for tumorsphere formation and metastatic spread

Molecular Oncology
High‐grade serous ovarian cancer (HGSOC) is the deadliest gynecological malignancy. The most common form of metastatic spread of HGSOC is transcoelomic dissemination.
Núria Gendrau‐Sanclemente, Agnès Figueras, Kristina Gracova, Álvaro Lahiguera, Elisenda Alsina‐Sanchís, Juan A. Marín‐Jiménez, August Vidal, Xavier Matias‐Guiu, Sergi Fernandez‐Gonzalez, Marc Barahona, Lola Martí, Jordi Ponce, Francesc Viñals   +12 more
doaj   +1 more source

Fibronectin Fibrillogenesis During Angiogenesis

, 2022
Vascular basement membrane is a critical regulator of angiogenesis. Fibronectin, a component of the vascular matrix, acts as a scaffold between the endothelial and perivascular cells that guide the assembly of other matrix components like the laminins ...
Ramesh, Lariza, Nair, Nidhi, Sundararaman, Ananthalakshmy, Gan, Xiangyi   +3 more
core   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Fibronectin-Collagen-T-antigen (FCT) region organization of FCT types 1 and 3.

, 2016
FCT-1 (SP8) was identified in only one of the isolates whereas FCT-3 was seen in all of the rest. The region is flanked by a chaperon (hsp33) and a hypothetical protein (hyp).
Jonathan A. Eisen (93505), David A. Coil (2226292), Guillaume Jospin (3559613), Sima Tokajian (3559616), Joe Ibrahim (3559610), Georges Khazen (171939)   +5 more
core   +1 more source

From Fiber Bundles to Architected Membranes: Triply Periodic Minimal Surface Architectures for Biohybrid Artificial Lungs

Advanced Materials, EarlyView.
Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Michael Pflaum, Kai P. Barbian, Florian Neuhaus, Gerrit Sitarz, Carolin Nölke, Sebastian V. Jansen, John Linkhorst, Lukas T. Hirschwald, Sebastian Brosch, Christian Certa, Ulrich Steinseifer, Matthias Wessling, Jutta Arens, Arjang Ruhparwar, Bettina Wiegmann   +14 more
wiley   +1 more source

Co-culture of Umbilical Cord-derived Hematopoietic and Mesenchymal Stem Cells on Protein-Coated poly-L-Lactic Acid Nanoscaffolds

Journal of Mazandaran University of Medical Sciences, 2020
Background and purpose: Umbilical cord blood (UCB) is a source of Hematopoietic stem cells (HSCs) and has received a lot of attention due to its availability, renewal capacity, proliferation rate, and differentiation potential.
Maryam Islami, Masoud Soleimani, Monireh Ajami, Maryam Darvish   +3 more
doaj  

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell‐Mediated Collagen Deposition in Engineered Cartilage

Advanced Materials, EarlyView.
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner, Lennard Spauwen, James L. Martin Robinson, Ángela García Grech, Isabelle Martinier, Sara Grasselli, Aylin Kara Özenler, Matthias Ryma, Jürgen Groll, Mylène de Ruijter, Jos Malda   +10 more
wiley   +1 more source