Results 111 to 120 of about 247,327 (296)

Conditional interactions of fibronectin: C-reactive protein, sulfated proteoglycans, and malignant transformation.

, 1983
Conditional interactions of fibronectin: C-reactive protein, sulfated proteoglycans, and malignant ...
Salonen E., Vartio T., BARLATI, Sergio, Vaheri A., DE PETRO, Giuseppina, Hedman K.   +5 more
core   +1 more source

Pericellular fibronectin is required for RhoA-dependent responses to cyclic strain in fibroblasts

, 2010
To test the hypothesis that the pericellular fibronectin matrix is involved in mechanotransduction, we compared the response of normal and fibronectin-deficient mouse fibroblasts to cyclic substrate strain.
Sakai, Takao, Lutz, Roman, Chiquet, Matthias   +2 more
core   +1 more source

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

Advanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai, Weikai Sun, Yuxuan Zhao, Daqian Sun, Ting Meng, Yafei Qi, Fengyang Jiang, Jintang Sun, Zhiliang Gao, Dexin Yu   +9 more
wiley   +1 more source

Contribution of hepatic fibronectin synthesis to regulation of plasma fibronectin

, 1989
Intravenous injection of gelatinized particles, which are phagocytized by the reticuloendothelial system, elicits an acute depletion of plasma fibronectin followed by restoration to normal concentrations in 6-8 h and a rebound elevation at 24 h.
T. M. Saba, E. Cho, E. Lewis, P. A. Vincent   +3 more
core   +1 more source

From Displacement to Angle: Diamond‐Based 3D Rotation Sensing for High‐Precision Cellular Force Measurement

Advanced Science, EarlyView.
Cellular forces are traditionally inferred from displacement measurements, which lack rotational information and are constrained by linear model assumptions. This work replaces displacement with rotational angle for the fundamental mechanical readout.
Linjie Ma, Bicong Wang, Tai Nam Yip, Jiahua Zhang, Yicheng Wang, Luyao Zhang, Yong Hou, Yuan Lin, Zhiqin Chu   +8 more
wiley   +1 more source

Untensed fibronectin fibers: a novel hallmark of microthrombi

Frontiers in Cardiovascular Medicine
BackgroundMyocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) accounts for up to 15% of acute Myocardial Infarction (MI) cases and presents significant diagnostic and therapeutic challenges.
Arnaud Miéville, Petra Wolint, Nikola Cesarovic, Nikola Cesarovic, Volkmar Falk, Volkmar Falk, Viola Vogel   +6 more
doaj   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

Advanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang, Qiubo Chen, Shihai Lan, Liang Zhu, Shuaiyu Liu, Yan Xia, Yalu Zhang, Hanhui Yao, Yongman Liu, Shangquan Wu, Qingchuan Zhang   +10 more
wiley   +1 more source

Evidence For Fibronectin Role On Uterine Natural Killer Cells Migration, Proliferation, Differentiation And Survival During Pregnancy

, 2015
Fibronectin is an extracellular matrix component which has a crucial role in the establishment of a successful pregnancy. In this respectit plays an important function in cell migration.
do Amarante Paffaro A.M., Zavan B., Joazeiro P.P., Paffaro Jr. V.A., Yamada A.T.   +4 more
core