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Fibronectin and Its Receptors in Hematopoiesis
Cells, 2020 Fibronectin is a ubiquitous extracellular matrix protein that is produced by many cell types in the bone marrow and distributed throughout it. Cells of the stem cell niche produce the various isoforms of this protein.
Franziska Wirth +3 more
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Cells, 2022 The microenvironment of tumors is characterized by structural changes in the fibronectin matrix, which include increased deposition of the EDA isoform of fibronectin and the unfolding of the fibronectin Type III domains.
Anthony Ambesi +2 more
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Vietnam Journal of Science, Technology and Engineering, 2022 Fibronectin is an abundant and ubiquitous extracellular matrix component that regulates a wide range of cell functions by directly interacting with cell surface integrin receptors.
Khon Huynh
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Frontiers in Medicine, 2022 Atherosclerosis is the major cause of cardiovascular disease that is characterized by plaque formation in the blood vessel wall. Atherosclerotic plaques represent sites of chronic inflammation with diverse cell content that is shifted toward the ...
Daria M. Potashnikova +9 more
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eLife, 2021 Nanometer-scale properties of the extracellular matrix influence many biological processes, including cell motility. While much information is available for single-cell migration, to date, no knowledge exists on how the nanoscale presentation of ...
Jacopo Di Russo +5 more
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Fibronectin unfolding revisited: modeling cell traction-mediated unfolding of the tenth type-III repeat. [PDF]
PLoS ONE, 2008 Fibronectin polymerization is essential for the development and repair of the extracellular matrix. Consequently, deciphering the mechanism of fibronectin fibril formation is of immense interest.
Elaine P S Gee +2 more
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Wnt5A modulates integrin expression in a receptor-dependent manner in ovarian cancer cells
Scientific Reports, 2021 Wnt5A signals through various receptors that confer versatile biological functions. Here, we used Wnt5A overexpressing human ovarian SKOV-3 and OVCAR-3 stable clones for assessing integrin expression, cell proliferation, migration, invasion, and the ...
Vajihe Azimian-Zavareh +5 more
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The role of IgE-receptors in IgE-dependent airway smooth muscle cell remodelling. [PDF]
PLoS ONE, 2013 BACKGROUND: In allergic asthma, IgE increases airway remodelling but the mechanism is incompletely understood. Airway remodelling consists of two independent events increased cell numbers and enhanced extracellular matrix deposition, and the mechanism by
Michael Roth +5 more
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Frontiers in Cellular and Infection Microbiology, 2021 Trypanosoma cruzi infection in humans leads to progression to chronic chagasic myocarditis (CCM) in 30% of infected individuals, paralleling T cell inflammatory infiltrates in the heart tissue.
Luiz Ricardo Berbert +11 more
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Fibrotic remodeling of the extracellular matrix through a novel (engineered, dual-function) antibody reactive to a cryptic epitope on the N-terminal 30 kDa fragment of fibronectin. [PDF]
PLoS ONE, 2013 Fibrosis is characterized by excessive accumulation of scar tissue as a result of exaggerated deposition of extracellular matrix (ECM), leading to tissue contraction and impaired function of the organ.
Maryada Sharma +6 more
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