Results 21 to 30 of about 665,801 (246)

Cost-effectiveness of fibronectin testing in a triage in women with threatened preterm labor: alleviation of pregnancy outcome by suspending tocolysis in early labor (APOSTEL-I trial) [PDF]

open access: yes, 2009
BACKGROUND: At present, women with threatened preterm labor before 32 weeks of gestation are, after transfer to a perinatal center, treated with tocolytics and corticosteroids. Many of these women are treated unnecessarily.
van Pampus Maria G   +131 more
core   +6 more sources

Short Hairpin RNA-Mediated Fibronectin Knockdown Delays Tumor Growth in a Mouse Glioma Model

open access: yesNeoplasia: An International Journal for Oncology Research, 2010
Glioblastoma multiforme is the most common and lethal primary brain tumor. Glioma progression depends on the rapid proliferation of tumor cells accompanied by an acute immunosuppressive environment, facilitated mainly by tumor infiltration of regulatory ...
Sadhak Sengupta   +5 more
doaj   +1 more source

Inhibitors of Human Neuraminidase Enzymes Block Transmigration in vitro

open access: yesFrontiers in Molecular Biosciences, 2022
Cell migration to a site of inflammation is an important step of the immune response. This process is coordinated by cytokines, receptors, and the signal processing machinery of the cell.
Md. Amran Howlader   +2 more
doaj   +1 more source

Resistance to the mTOR Inhibitor Temsirolimus Alters Adhesion and Migration Behavior of Renal Cell Carcinoma Cells through an Integrin α5– and Integrin β3–Dependent Mechanism

open access: yesNeoplasia: An International Journal for Oncology Research, 2014
Inhibitors of the mammalian target of rapamycin (mTOR) have improved the treatment of renal cell carcinoma (RCC). However, chronic drug exposure may trigger resistance, limiting the utility of these agents.
Eva Juengel   +7 more
doaj   +1 more source

Evaluation of Renoprotective Effect of Lipoic Acid and Bosentan Against Diclofenac-Induced Acute Renal Failure

open access: yesIraqi Journal of Pharmaceutical Sciences, 2023
Acute renal failure also known as acute kidney injury (AKI) is a complex health condition related to significant morbidity and mortality. In hospitalized patients, around 19-33 percent of AKI episodes are linked to drug induced nephrotoxicity.
Lina Al-Hasani   +2 more
doaj   +1 more source

Levels of isoforms of fibronectin and α5/CD49e integrin on lymphocytes and in blood plasma in the conditions of chronic diffuse liver diseases

open access: yesRegulatory Mechanisms in Biosystems, 2020
Chronic diffuse liver diseases are characterized by accumulation of complex inflammatory infiltrate in the liver tissues, blood, and lympha, and activation of the immune system.
H. V. Dolhikh   +4 more
doaj   +1 more source

Minimal structural elements required for midline repulsive signaling and regulation of Drosophila Robo1.

open access: yesPLoS ONE, 2020
The Roundabout (Robo) family of axon guidance receptors has a conserved ectodomain arrangement of five immunoglobulin-like (Ig) domains plus three fibronectin type III (Fn) repeats.
Haley E Brown, Timothy A Evans
doaj   +1 more source

Inhibition of αvβ3 integrin induces loss of cell directionality of oral squamous carcinoma cells (OSCC). [PDF]

open access: yesPLoS ONE, 2017
The connective tissue formed by extracellular matrix (ECM) rich in fibronectin and collagen consists a barrier that cancer cells have to overpass to reach blood vessels and then a metastatic site. Cell adhesion to fibronectin is mediated by αvβ3 and α5β1
Cyntia F Montenegro   +7 more
doaj   +1 more source

Cell adhesion and signaling on the fibronectin 1st type III repeat; requisite roles for cell surface proteoglycans and integrins

open access: yesBMC Cell Biology, 2001
Background The first type III repeat of fibronectin is known to be involved in fibronectin matrix assembly, and recombinant proteins from this type III repeat can inhibit cell proliferation, tumor metastasis and angiogenesis. We have analyzed the way rat
Morla Alex O, Mercurius Kwesi O
doaj   +1 more source

Novel potential interacting partners of fibronectin in spontaneous animal model of interstitial cystitis [PDF]

open access: yes, 2012
Feline idiopathic cystitis (FIC) is the only spontaneous animal model for human interstitial cystitis (IC), as both possess a distinctive chronical and relapsing character. Underlying pathomechanisms of both diseases are not clearly established yet.
Amann, Barbara   +30 more
core   +2 more sources

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