Results 21 to 30 of about 91,178 (265)
Inhibitors of Human Neuraminidase Enzymes Block Transmigration in vitro
Frontiers in Molecular Biosciences, 2022 Cell migration to a site of inflammation is an important step of the immune response. This process is coordinated by cytokines, receptors, and the signal processing machinery of the cell.
Md. Amran Howlader +2 more
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Short Hairpin RNA-Mediated Fibronectin Knockdown Delays Tumor Growth in a Mouse Glioma Model
Neoplasia: An International Journal for Oncology Research, 2010 Glioblastoma multiforme is the most common and lethal primary brain tumor. Glioma progression depends on the rapid proliferation of tumor cells accompanied by an acute immunosuppressive environment, facilitated mainly by tumor infiltration of regulatory ...
Sadhak Sengupta +5 more
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Purification of the β subunit of the fibronectin receptor [PDF]
European Journal of Biochemistry, 1988 In this work we describe a method for purification of the β subunit of the mouse fibronectin receptor (CP135). Cellular glycoproteins were isolated from a detergent extract of SR‐Balb tumor cell membranes by two steps of affinity chromatography on lentil lectin‐Sepharose and wheat‐germ‐agglutinin–agarose. This material was subsequently bound to an Affi
G, Tarone +3 more
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Neoplasia: An International Journal for Oncology Research, 2014 Inhibitors of the mammalian target of rapamycin (mTOR) have improved the treatment of renal cell carcinoma (RCC). However, chronic drug exposure may trigger resistance, limiting the utility of these agents.
Eva Juengel +7 more
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Regulation of fibronectin by thyroid hormone receptors [PDF]
Journal of Molecular Endocrinology, 2004 Thyroid hormones regulate growth, development, differentiation, and metabolic processes by interacting with and activating thyroid hormone receptors and associated pathways. We investigated the triiodothyronine (T3) modulation of gene expression, in human hepatocellular carcinoma cell lines, via a PCR-based cDNA subtraction method.
Kwang-Huei, Lin +8 more
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Iraqi Journal of Pharmaceutical Sciences, 2023 Acute renal failure also known as acute kidney injury (AKI) is a complex health condition related to significant morbidity and mortality. In hospitalized patients, around 19-33 percent of AKI episodes are linked to drug induced nephrotoxicity.
Lina Al-Hasani +2 more
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Regulatory Mechanisms in Biosystems, 2020 Chronic diffuse liver diseases are characterized by accumulation of complex inflammatory infiltrate in the liver tissues, blood, and lympha, and activation of the immune system.
H. V. Dolhikh +4 more
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PLoS ONE, 2020 The Roundabout (Robo) family of axon guidance receptors has a conserved ectodomain arrangement of five immunoglobulin-like (Ig) domains plus three fibronectin type III (Fn) repeats.
Haley E Brown, Timothy A Evans
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Inhibition of αvβ3 integrin induces loss of cell directionality of oral squamous carcinoma cells (OSCC). [PDF]
PLoS ONE, 2017 The connective tissue formed by extracellular matrix (ECM) rich in fibronectin and collagen consists a barrier that cancer cells have to overpass to reach blood vessels and then a metastatic site. Cell adhesion to fibronectin is mediated by αvβ3 and α5β1
Cyntia F Montenegro +7 more
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Fibronectin and Fibronectin Receptors in Lung Development
Experimental Lung Research, 1997 Fibronectin (FN) is a cell adhesive extracellular matrix protein highly expressed in developing lungs. Although the role of FN in lung development remains to be elucidated, several observations suggest that it plays important roles in many developmental processes. In vitro, FN can affect the migration, proliferation, differentiation, and even apoptosis
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