Results 11 to 20 of about 91,178 (265)

Circulating fibronectin and fibronectin receptor in children with pertussis. [PDF]

Journal of Clinical Pathology, 1994
AIM--To determine concentrations of fibronectin and fibronectin receptor in children with pertussis. METHODS--Concentrations of circulating fibronectin and serum fibronectin receptor were detected in eight children affected by pertussis, eight children with acute upper or lower respiratory tract infections, and in 14 healthy control children.
D, Torre, M, Giola, C, Zeroli, R, Martegani, G, Bonetta, G, Ferrario   +5 more
openaire   +2 more sources

Enhanced Migratory Capacity of T Lymphocytes in Severe Chagasic Patients Is Correlated With VLA-4 and TNF-α Expression

Frontiers in Cellular and Infection Microbiology, 2021
Trypanosoma cruzi infection in humans leads to progression to chronic chagasic myocarditis (CCM) in 30% of infected individuals, paralleling T cell inflammatory infiltrates in the heart tissue.
Luiz Ricardo Berbert, Florencia Belén González, Silvina Raquel Villar, Carlos Vigliano, Susana Lioi, Juan Beloscar, Oscar Adelmo Bottasso, Suse Dayse Silva-Barbosa, Wilson Savino, Wilson Savino, Wilson Savino, Ana Rosa Pérez   +11 more
doaj   +1 more source

Fibrotic remodeling of the extracellular matrix through a novel (engineered, dual-function) antibody reactive to a cryptic epitope on the N-terminal 30 kDa fragment of fibronectin. [PDF]

PLoS ONE, 2013
Fibrosis is characterized by excessive accumulation of scar tissue as a result of exaggerated deposition of extracellular matrix (ECM), leading to tissue contraction and impaired function of the organ.
Maryada Sharma, Anil Tiwari, Shweta Sharma, Preeti Bhoria, Vishali Gupta, Amod Gupta, Manni Luthra-Guptasarma   +6 more
doaj   +1 more source

Molecular Docking Characterization of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop with Hydroxyapatite

Molecules, 2013
Fibronectin adsorption on biomaterial surfaces plays a key role in the biocompatibility of biomedical implants. In the current study, the adsorption behavior of the 7–10th type III modules of fibronectin (FN-III7–10) in the presence of hydroxyapatite ...
Tailin Guo, Wenyuan Kang, Dongqin Xiao, Rongquan Duan, Wei Zhi, Jie Weng   +5 more
doaj   +1 more source

Microglial inflammation after chronic spinal cord injury is enhanced by reactive astrocytes via the fibronectin/β1 integrin pathway

Journal of Neuroinflammation, 2021
Background After spinal cord injury (SCI), glial scarring is mainly formed around the lesion and inhibits axon regeneration. Recently, we reported that anti-β1 integrin antibody (β1Ab) had a therapeutic effect on astrocytes by preventing the induction of
Shingo Yoshizaki, Tetsuya Tamaru, Masamitsu Hara, Ken Kijima, Masatake Tanaka, Dai-jiro Konno, Yoshihiro Matsumoto, Yasuharu Nakashima, Seiji Okada   +8 more
doaj   +1 more source

Expression of fibronectin, fibronectin isoforms and integrin receptors in melanocytic lesions [PDF]

British Journal of Cancer, 1995
In vitro studies have demonstrated that fibronectin (FN) can deliver a mitogenic signal to quiescent human melanoma cells and that the alpha 5/beta 1-integrin receptor mediates this stimulus. In view of this finding we have analysed the in vivo expression of FN, and of ED-A and ED-B FN isoforms, in benign and malignant lesions of melanocyte origin.
P G, Natali, M R, Nicotra, F, Di Filippo, A, Bigotti   +3 more
openaire   +2 more sources

HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway

Skeletal Muscle, 2017
Background The hepatocyte growth factor (HGF) is required for the activation of muscle progenitor cells called satellite cells (SC), plays a role in the migration of proliferating SC (myoblasts), and is present as a soluble factor during muscle ...
Mariela Natacha González, Wallace de Mello, Gillian S. Butler-Browne, Suse Dayse Silva-Barbosa, Vincent Mouly, Wilson Savino, Ingo Riederer   +6 more
doaj   +1 more source

The Staphylococcus aureus Receptor for Fibronectin

Journal of Investigative Dermatology, 1983
The Staphylococcus aureus binding site for human fibronectin was determined by unique biologic assays based upon the specific adherence of the bacterium to nasal epithelial cells. Fibronectin treatment of S. aureus caused a reduction in adherence tallies on high granular and fully keratinized cells compared to controls (p less than 0.05; p less than 0 ...
Bibel, Debra Jan, Aly, Raza, Shinefield, Henry R., Maibach, Howard I.   +3 more
openaire   +2 more sources

Fibronectin binding determinants of the Staphylococcus aureus fibronectin receptor

Journal of Biological Chemistry, 1991
Synthetic peptide analogs mimicking a repeated motif within the Staphylococcus aureus fibronectin receptor inhibit binding of the bacteria to fibronectin (Signäs, C., Raucci, G., Jonsson, K., Lindgren, P. E., Anantharamaiah, G. M., Höök, M., and Lindberg, M. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 699-703). In this study, we have further localized the
M J, McGavin, G, Raucci, S, Gurusiddappa, M, Höök   +3 more
openaire   +2 more sources

Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors.

PLoS ONE, 2015
Binding of α5β1 and αvβ3/β5 integrin receptors on the endothelium to their fibronectin substrate in the extracellular matrix has been targeted as a possible means of blocking tumor angiogenesis and tumor growth.
Patrick A Murphy, Shahinoor Begum, Richard O Hynes   +2 more
doaj   +1 more source