Results 11 to 20 of about 665,801 (246)

Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors. [PDF]

PLoS ONE, 2015
Binding of α5β1 and αvβ3/β5 integrin receptors on the endothelium to their fibronectin substrate in the extracellular matrix has been targeted as a possible means of blocking tumor angiogenesis and tumor growth.
Patrick A Murphy, Shahinoor Begum, Richard O Hynes   +2 more
doaj   +2 more sources

Structural and functional studies of intrinsically disordered fibronectin-binding proteins [PDF]

, 2009
Bacterial fibronectin-binding proteins (FnBPs) mediate adhesion of bacteria to host tissues through binding to the human protein fibronectin (Fn). FnBPs are predicted to contain a series of intrinsically disordered Fn-binding repeats (FnBRs), which ...
Norris, Nicole Catherine
core   +6 more sources

Outer Membrane Protein YadA of Enteropathogenic Yersiniae Mediates Specific Binding to Cellular but Not Plasma Fibronectin [PDF]

, 1993
The binding of bacteria or bacterial products to host proteins of tissue extracellular matrix may be a mechanism of tissue adherence. We investigated interactions of the plasmid-encoded outer membrane protein YadA, which confers pathogenic functions on ...
Emmerich, F., Burkhardt, H., Kirsch, T., Schulze-Koops, Hendrik, Swoboda, B., Bull, C., Goodman, S., Heesemann, Jürgen   +7 more
core   +1 more source

Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]

, 1994
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Ritter, Christoph von, Lange, Volker, Del Pozo, Reginals, Paumgartner, Gustav, V. Lange, J. F. Miquel, R. Del Pozo, G. Paumgartner, Jüngst, Dieter, Miquel, Juan Francisco, C. Von Ritter, D. Jungst   +11 more
core   +1 more source

Fibronectin III 13-14 Domains Induce Joint Damage via Toll-Like Receptor 4 Activation and Synergize with Interleukin-1 and Tumour Necrosis Factor [PDF]

, 2011
Cartilage loss is a feature of chronic arthritis. It results from degradation of the extracellular matrix which is composed predominantly of aggrecan and type II collagen.
Saralili Dipa Robertson, Sofat, N, Nidhi Sofat, Wait, R, Robertson, SD, Wait, Robin, Robin Wait   +6 more
core   +1 more source

Staphylococcus aureus-Fibronectin Interactions with and without Fibronectin-Binding Proteins and Their Role in Adhesion and Desorption [PDF]

, 2008
Adhesion and residence-time-dependent desorption of two Staphylococcus aureus strains with and without fibronectin (Fn) binding proteins (FnBPs) on Fn-coated glass were compared under flow conditions.
Boks, N.P., Norde, Willem, Busscher, Hendrik, Busscher, H.J., Vries, J., de, Xu, C.P., Mei, H.C., van der, van der Mei, Henderina; id_orcid, Kaper, Harm, Norde, W., Xu, Chun, Boks, Niels P, de Vries, Jacob; id_orcid, Kaper, H.J.   +13 more
core   +1 more source

Molecular Docking Characterization of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop with Hydroxyapatite

Molecules, 2013
Fibronectin adsorption on biomaterial surfaces plays a key role in the biocompatibility of biomedical implants. In the current study, the adsorption behavior of the 7–10th type III modules of fibronectin (FN-III7–10) in the presence of hydroxyapatite ...
Tailin Guo, Wenyuan Kang, Dongqin Xiao, Rongquan Duan, Wei Zhi, Jie Weng   +5 more
doaj   +1 more source

Microglial inflammation after chronic spinal cord injury is enhanced by reactive astrocytes via the fibronectin/β1 integrin pathway

Journal of Neuroinflammation, 2021
Background After spinal cord injury (SCI), glial scarring is mainly formed around the lesion and inhibits axon regeneration. Recently, we reported that anti-β1 integrin antibody (β1Ab) had a therapeutic effect on astrocytes by preventing the induction of
Shingo Yoshizaki, Tetsuya Tamaru, Masamitsu Hara, Ken Kijima, Masatake Tanaka, Dai-jiro Konno, Yoshihiro Matsumoto, Yasuharu Nakashima, Seiji Okada   +8 more
doaj   +1 more source

Immunohistochemical localization of fibronectin as a tool for the age determination of human skin wounds [PDF]

, 1992
We analyzed the distribution of fibronectin in routinely embedded tissue specimens from 53 skin wounds and 6 postmortem wounds. In postmortem wounds a faint but focal positive staining was exclusively found at the margin of the specimens which dit not ...
Penning, R., Eisenmenger, Wolfgang, J. Tübel, J. Wilskel, A. Nerlich, W. Eisenmenger, Tübel, J., Wilske, J., Wiest, I., R. Penning, Nerlich, A., I. Wiest, P. Betz, Betz, P.   +13 more
core   +1 more source

HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway

Skeletal Muscle, 2017
Background The hepatocyte growth factor (HGF) is required for the activation of muscle progenitor cells called satellite cells (SC), plays a role in the migration of proliferating SC (myoblasts), and is present as a soluble factor during muscle ...
Mariela Natacha González, Wallace de Mello, Gillian S. Butler-Browne, Suse Dayse Silva-Barbosa, Vincent Mouly, Wilson Savino, Ingo Riederer   +6 more
doaj   +1 more source