Results 71 to 80 of about 323,080 (292)

Interaction of integrin αvβ3 and fibronectin under fluid shear forces: implications for tumor cell adhesion and migration

Frontiers in Cell and Developmental Biology
The interaction between integrin αvβ3 and fibronectin enables tumor cell adherence to endothelial layers under diverse hydrodynamic blood flow conditions, particularly in low shear stress regions.
Paimin Zhuo, Quhuan Li, Bishan Yang, Bishan Yang, Na Li, Zhiqing Luo, Fengxia Zhang   +6 more
doaj   +1 more source

Lysophosphatidic acid induces integrin activation in vascular smooth muscle and alters arteriolar myogenic vasoconstriction

Frontiers in Physiology, 2014
In vascular smooth muscle cells (VSMC) increased integrin adhesion to extracellular matrix (ECM) proteins, as well as the production of reactive oxygen species (ROS) are strongly stimulated by lysophosphatidic acid (LPA). We hypothesized that LPA-induced
Marius C. Staiculescu, Francisco I. Ramirez-Perez, Francisco I. Ramirez-Perez, Jorge A. Castorena-Gonzalez, Jorge A. Castorena-Gonzalez, Zhongkui eHong, Zhe eSun, Gerald A. Meininger, Gerald A. Meininger, Gerald A. Meininger, Luis A. Martinez-Lemus, Luis A. Martinez-Lemus, Luis A. Martinez-Lemus   +12 more
doaj   +1 more source

Adhesion of endothelial cells and adsorption of serum proteins on gas plasma-treated polytetrafluoroethylene [PDF]

, 1991
From in vitro experiments it is known that human endothelial cells show poor adhesion to hydrophobic polymers. The hydrophobicity of vascular prostheses manufactured from Teflon® or Dacron® may be the reason why endothelialization of these grafts does ...
Aken, W.G. van, Bantjes, A., Beugeling, T., Dekker, A., Feijen, J., Reitsma, K.   +5 more
core   +2 more sources

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Fibronectin Functionalized Electrospun Fibers by Using Benign Solvents: Best Way to Achieve Effective Functionalization

Frontiers in Bioengineering and Biotechnology, 2019
The aim of this study is to demonstrate the feasibility of different functionalization methods for electrospun fibers developed using benign solvents.
Liliana Liverani, Manuela S. Killian, Aldo R. Boccaccini   +2 more
doaj   +1 more source

Current approaches for modulation of the nanoscale interface in the regulation of cell behavior [PDF]

, 2018
Regulation of cell behavior in response to nanoscale features has been the focus of much research in recent years and the successful generation of nanoscale features capable of mimicking the natural nanoscale interface has been of great interest in the ...
Dalby, Matthew J., Donnelly, Hannah, Salmeron-Sanchez, Manuel, Sweeten, Paula E.   +3 more
core   +1 more source

Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation

Advanced Functional Materials, EarlyView.
Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu, Joel Aboagye, Marcella Edwards, Nick Rogozinski, Yufeng Wen, Angello Huerta Gomez, Zui Pan, Ge Zhang, Huaxiao Yang, Yi Hong   +9 more
wiley   +1 more source

Modulation of fibronectin extracellular matrix enhances anti-tumor efficacy of immune checkpoint blockade

Cell Reports Medicine
Summary: The success of immune checkpoint inhibitors is limited by multiple factors, including poor T cell infiltration and function within tumors, partly due to a dense extracellular matrix (ECM).
Kabir A. Khan, Maresa Caunt Mitzner, William Cruz-Munoz, Grant Li, Patricia Himmels, Ping Xu, Hung Yang Kuo, Raj Jesudason, Alvin Gogineni, Robby Weimer, Annabelle Chow, Robert Piskol, Iacovos P. Michael, Weilan Ye, Robert S. Kerbel   +14 more
doaj   +1 more source

The Induction of EMT and Activation of Adipose Stem Cells in Correlation with the Secretion of LTBP-1 in Mammary Cells [PDF]

, 2015
This work is part of an ongoing study that investigates the upregulation of LTBP-1 in mammary epithelial cells as well as the differentiation of breast adipose stem cells (BASCs) in the presence of TGF-β1.
Griggs, Lauren, Lemmon, Dr. Christopher, PhD, Malik, Roshni   +2 more
core   +1 more source

Vitronectin as a micromanager of cell response in material-driven fibronectin nanonetworks [PDF]

, 2017
Surface functionalization strategies of synthetic materials for regenerative medicine applications comprise the development of microenvironments that recapitulate the physical and biochemical cues of physiological extracellular matrices. In this context,
Altankov, Arima, Ballester-Beltran, Barrias, Barrère, Bathawab, Bornstein, Cantini, Chaturvedi, Crowder, Erickson, Erickson, Fabrizius-Homan, Felding-Habermann, Felgueiras, García, Gonzalez-Garcia, Guan, Guerra, Gugutkov, Gugutkov, Hinderer, Izumi, Kalaskar, Kamikubo, Keselowsky, Leahy, Leavesley, Llopis-Hernandez, Llopis-Hernández, Madsen, Malmstrom, Mao, Martino, Martino, Minor, Missirlis, Molnar, Nelea, Noh, Pankov, Pankov, Pearlstein, Podor, Pompe, Pompe, Preissner, Rico, Rico, Sabater, Salmeron-Sanchez, Salmeron-Sanchez, Schwarzbauer, Selinummi, Steele, Stockmann, Toromanov, Underwood, Vanterpool, Vaz, Vyner, Wilson, Wu, Xu, Yap, Zanetti, Zhang   +66 more
core   +1 more source