Results 251 to 260 of about 333,512 (335)

DIRAS3 Inhibits Ovarian Cancer Cell Growth by Blocking the Fibronectin-Mediated Integrin β1/FAK/AKT Signaling Pathway. [PDF]

open access: yesCells
Guo J   +9 more
europepmc   +1 more source

Enzymochemical Studies on Pancreatic Elastase. II. Actions of Hog Pancreatic Elastase I on Fibronectin

open access: bronze, 1984
Toshihiko Nagai   +4 more
openalex   +2 more sources

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

open access: yesAdvanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou   +14 more
wiley   +1 more source

Effect of IL-1β on NSCLC-Derived Small Extracellular Vesicles as Actors in Mediating Cancer Progression and Evading Immune System. [PDF]

open access: yesInt J Mol Sci
Heydari Sheikhhossein H   +19 more
europepmc   +1 more source

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

open access: yesAdvanced Science, EarlyView.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye   +11 more
wiley   +1 more source

Fibronectin receptors from Staphylococcus aureus.

open access: hybrid, 1983
Cécilia Rydèn   +5 more
openalex   +1 more source

Succinic Acid‐Induced Macrophage Endocytosis Promotes Extracellular Vesicle‐Based Integrin Beta1 Transfer Accelerating Fibroblast Activation and Sepsis‐Associated Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
Lipopolysaccharide (LPS) stimulates the production of succinic acid in lung tissue, which promotes macrophages endocytosis and the formation of multivesicular bodies (MVBs). These MVBs release profibrotic extracellular vesicles (EVs), facilitating the transfer of integrin beta1 (ITGβ1) transfer and subsequently activating fibroblasts, thereby ...
Wenyu Yang   +10 more
wiley   +1 more source

EPEC autotransporter adhesin (Eaa): a novel adhesin identified in atypical enteropathogenic <i>Escherichia coli</i>. [PDF]

open access: yesFront Cell Infect Microbiol
Orsi H   +13 more
europepmc   +1 more source

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