Results 41 to 50 of about 333,512 (335)

Mechanical forces regulate the interactions of fibronectin and collagen I in extracellular matrix [PDF]

, 2015
Despite the crucial role of extracellular matrix (ECM) in directing cell fate in healthy and diseased tissues--particularly in development, wound healing, tissue regeneration and cancer--the mechanisms that direct the assembly and regulate hierarchical ...
Gourdon, Delphine, Klotzsch, Enrico, Kubow, Kristopher E., Luna, Sheila, Smith, Michael L., Vogel, Viola, Vukmirovic, Radmila, Zhe, Lin   +7 more
core   +2 more sources

Fibronectin-Enriched Biomaterials, Biofunctionalization, and Proactivity: A Review

Applied Sciences, 2021
Modern innovation in reconstructive medicine implies the proposition of material-based strategies suitable for tissue repair and regeneration. The development of such systems necessitates the design of advanced materials and the control of their ...
Carla Palomino-Durand, Emmanuel Pauthe, Adeline Gand   +2 more
doaj   +1 more source

Functional differences between two morphologically distinct cell subpopulations within a human colorectal carcinoma cell line

Brazilian Journal of Medical and Biological Research, 2001
The LISP-I human colorectal adenocarcinoma cell line was isolated from a hepatic metastasis at the Ludwig Institute, São Paulo, SP, Brazil. The objective of the present study was to isolate morphologically different subpopulations within the LISP-I cell ...
A.C.C. Solimene, C.R.W. Carneiro, I. Melati, J.D. Lopes   +3 more
doaj   +1 more source

PL1 Peptide Engages Acidic Surfaces on Tumor-Associated Fibronectin and Tenascin Isoforms to Trigger Cellular Uptake

Pharmaceutics, 2021
Tumor extracellular matrix (ECM) is a high-capacity target for the precision delivery of affinity ligand-guided drugs and imaging agents. Recently, we developed a PL1 peptide (sequence: PPRRGLIKLKTS) for systemic targeting of malignant ECM.
Prakash Lingasamy, Kristina Põšnograjeva, Sergei Kopanchuk, Allan Tobi, Ago Rinken, Ignacio J. General, Eliana K. Asciutto, Tambet Teesalu   +7 more
doaj   +1 more source

Models of fibronectin. [PDF]

The EMBO Journal, 1987
The radius of gyration of human plasma fibronectin was determined by light scattering both under conditions in which the molecule is in an extended conformation (ionic strength 1.01 M, pH 8) and close to its native, more compact conformation (ionic strength 0.16 M, pH 8).
L. Gogioso, E. Infusini, M. G. Daga, Carla Cuniberti, Mattia Rocco   +4 more
openaire   +3 more sources

Fibronectin and Periostin as Prognostic Markers in Ovarian Cancer

Cells, 2020
Previously, based on a DNA microarray experiment, we identified a 96-gene prognostic signature associated with the shorter survival of ovarian cancer patients.
Katarzyna Aleksandra Kujawa, Ewa Zembala-Nożyńska, Alexander Jorge Cortez, Tomasz Kujawa, Jolanta Kupryjańczyk, Katarzyna Marta Lisowska   +5 more
doaj   +1 more source

CD9 co-operation with syndecan-1 is required for a major staphylococcal adhesion pathway

mBio, 2023
Epithelial colonization is a critical first step in bacterial pathogenesis. Staphylococcus aureus can utilize several host factors to associate with cells, including α5β1 integrin and heparan sulfate proteoglycans, such as the syndecans.
Luke R. Green, Rahaf Issa, Fawzyah Albaldi, Lucy Urwin, Ruth Thompson, Henna Khalid, Claire E. Turner, Barbara Ciani, Lynda J. Partridge, Peter N. Monk   +9 more
doaj   +1 more source

Biomimetic implant surface functionalization with liquid L-PRF products: in vitro study [PDF]

, 2018
Objective: Platelet-rich fibrin (PRF) clots and membranes are autologous blood concentrates widely used in oral surgical procedures; less is known, however, about the liquid formulations of such products.
BOZZUTO, GIUSEPPINA, DE BIASE, Alberto, Formisano, Giuseppe, Lollobrigida, Marco, Maritato, Manuela, Molinari, Agnese   +5 more
core   +2 more sources

Circulating fibronectin and fibronectin receptor in children with pertussis. [PDF]

Journal of Clinical Pathology, 1994
To determine concentrations of fibronectin and fibronectin receptor in children with pertussis.Concentrations of circulating fibronectin and serum fibronectin receptor were detected in eight children affected by pertussis, eight children with acute upper or lower respiratory tract infections, and in 14 healthy control children.
D Torre, M Giola, R Martegani, G Bonetta, G Ferrario, C Zeroli   +5 more
openaire   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source