Results 91 to 100 of about 8,122 (251)
The Journal of Cell Biology, 2003 ![Graphic][1] FN (green) suppresses cadherins (red) and promotes cell–matrix adhesions during branching. Yamada/MacmillanBranched organs are shaped when epithelia make their own paths, according to a study by Takayoshi Sakai, Melinda Larsen, and Kenneth Yamada (National ...
openaire +3 more sources
Imine Crosslinked, Injectable, and Self‐Healing Fucoidan Hydrogel with Immunomodulatory Properties
Advanced Healthcare Materials, EarlyView.This study develops an injectable fucoidan‐based hydrogel with tunable properties for tissue engineering. By oxidizing fucoidan (OFu) to introduce aldehydes, imine crosslinks are formed with amine‐containing polymers, enabling self‐healing, injectability, and long‐term stability (≥28 days). The OFu‐gelatin hydrogel demonstrated biocompatibility, immune‐
Asma Talib Qureshi +3 more
wiley +1 more source
A Bio‐Inspired Perspective on Materials Sustainability
Advanced Materials, EarlyView.This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier +2 more
wiley +1 more source
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
Advanced Materials, EarlyView.We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin +17 more
wiley +1 more source
Multiscale Modelling of Fibres Dynamics and Cell Adhesion within Moving Boundary Cancer Invasion [PDF]
arXiv, 2018 Cancer cell invasion is recognised as one of the hallmarks of cancer and involves several inner-related multiscale processes that ultimately contribute to its spread into the surrounding tissue. In order to gain a deeper understanding of the tumour invasion process, we pay special attention to the interacting dynamics between the cancer cell population
arxiv
Biomimetic Dynamics of Nanoscale Groove and Ridge Topography for Stem Cell Regulation
Advanced Materials, EarlyView.Dynamic nanoscale groove‐ridge structures are engineered by flexibly conjugating RGD‐magnetic nanoparticles to nanogroove templates with variable groove widths at the molecular scale. Magnetic control enables cyclic switching between nanoscale groove and ridge states that modulates ligand accessibility of cellular integrins.
Hyunsik Hong +8 more
wiley +1 more source
Advanced Materials, EarlyView.Cancer metastasis begins with intravasation, a complex process involving cancer‐endothelial interactions. INVADE (Intravasation‐on‐µDevice), a biomimetic microfluidic platform enables high‐throughput analysis of intravasation under controlled conditions.
Fengtao Jiang +12 more
wiley +1 more source
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro +5 more
wiley +1 more source
Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration
Advanced Therapeutics, EarlyView.Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana +5 more
wiley +1 more source