Results 91 to 100 of about 86,137 (348)

A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions

Advanced Healthcare Materials, EarlyView.
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan, Partho Protim Adhikary, Dana Wörz, Sarah Hedtrich   +3 more
wiley   +1 more source

Simultaneous determination and association between serum levels of irisin and chemerin in PCOS

Journal of the Pakistan Medical Association
Objective: To determine the serum levels of irisin, chemerin and insulin in women with polycystic ovary syndrome, and to compare their levels with respect to bodyweight and body mass index.
Hajer Wahbi Abdullateef, Shatha Mohammed Al-khateeb, Esraa Hameed AL-Maini   +2 more
doaj   +1 more source

BS41 Enhancing cardiac regeneration: the role of fibronectin in stem cell-derived epicardial-cardiomyocyte crosstalk [PDF]

, 2022
Jonathan Chuo Min Lee, Lay Ping Ong, Semih Bayraktar, Patrick Rericha, Vincent Knight-Schrijver, Maria Colzani, Johannes Bargehr, Laure Gambardella, Sanjay Sinha   +8 more
openalex   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Biochemical versus radiological screening for osteoporosis in menopause; will Irisin help?

Journal of the Pakistan Medical Association
Objective: To verify the discriminative power of irisin in osteoporosis patients. Method: The comparative case-control study was conducted at the University Teaching Hospital, Baghdad, Iraq,from March 2020 to June 2021 after approval from the ethics ...
Wisam Akram, Alaa Ibrahim Ali, Hind Hadi Majeed   +2 more
doaj   +1 more source

Recipient‐derived EDA fibronectin promotes cardiac allograft fibrosis [PDF]

, 2012
Advances in donor matching and immunosuppressive therapies have decreased the prevalence of acute rejection of cardiac grafts; however, chronic rejection remains a significant obstacle for long‐term allograft survival.
Adair-Kirk, Arslan, Bishop, Boehler, Booth, Booth, Borsi, Broekelmann, Chan, Chan, Coito, Coito, Corry, Csencsits, Csencsits, Davis, Diaz, Dubin, Franz, Franz, Franz, Hernnas, Hornick, Jarnagin, Kohan, Kornblihtt, Korpos, Kuhn, Libby, Mannon, Mehra, Moretti, Muro, Muro, Nemzek, Okamura, Peters, Peters, Piccotti, Piccotti, Raichlin, Saito, Sandig, Serini, Thannickal, Thickett, Torre-Amione, Utsumi, White, White, Wood   +50 more
core   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

Effect of photodynamic therapy on the extracellular matrix and associated components [PDF]

, 2007
In many countries, photodynamic therapy (PDT) has been recognized as a standard treatment for malignant conditions (for example, esophageal and lung cancers) and non-malignant ones such as age-related macular degeneration and actinic keratoses.
Nader, Helena Bonciani, Pazos, Marcelo de Castro   +1 more
core   +2 more sources

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

Advanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee, Yuen Ting Lam, Alex H. P. Chan, Praveesuda L. Michael, Timothy C. Mitchell, Jui Chien Hung, Miguel Santos, Khoon S. Lim, Richard P. Tan, Steven G. Wise   +9 more
wiley   +1 more source

Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering

Advanced Healthcare Materials, EarlyView.
This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer, Arundhati Joshi, Constantin von Kaisenberg, Dorothea Brüggemann, Cornelia Lee‐Thedieck   +4 more
wiley   +1 more source