Results 31 to 40 of about 39,976 (222)
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source
Precision medicine in paediatrics: Progress and priorities
British Journal of Clinical Pharmacology, EarlyView.Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
Transformation of dermatofibrosarcoma protuberans into a fibrosarcoma
Indian Journal of Dermatology, 2016 Dermatofibrosarcoma protuberans is a rare cutaneous mesenchymal tumor characterized by a low potential of malignancy with a very low rate of metastasis but an important rate of local recurrence.
Mohamed Ali Sbai +4 more
doaj +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Malignant glioma is the most common primary brain tumor, and glioblastoma multiforme (GBM) remains its most aggressive and incurable form. Snake venoms contain bioactive compounds with promising antitumoral properties against several cancer types.
M. O. H. V. Rosário +7 more
wiley +1 more source
Early Social Enrichment Modulates Tumor Progression and p53 Expression in Adult Mice
Biomolecules, 2022 Epidemiological evidence indicates that stress and aversive psychological conditions can affect cancer progression, while well-being protects against it.
Silvia Middei +9 more
doaj +1 more source
The effects of royal jelly on human health: A narrative review of clinical studies
JSFA reports, EarlyView.Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras +2 more
wiley +1 more source
Materials Today BioFibrosarcoma is a kind of highly malignant sarcoma with high recurrence rate after surgery and unsatisfying efficacy of radiotherapy and chemotherapy. Increasing the concentration of gasdermin in tumor cell to induce pyroptosis is a promising strategy to
Fenglin Miao +12 more
doaj +1 more source
Fibrosarcoma in a Goldfish (Carassius auratus): a Case report [PDF]
The Iranian Journal of Veterinary Science and Technology, 2017 Neoplasms in fishes are generally less aggressive than neoplasms in mammals and are most commonly discrete and focal. Although tumors were originated from connective tissue are frequently seen in the fishes, but dermal fibrosarcoma is rarely found in fish.
Annahita Rezaie +2 more
doaj +1 more source
Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa +2 more
wiley +1 more source
Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report
Veterinární Medicína, 2012 An 11-year-old male Cocker Spaniel was examined for a palpable abdominal mass located in the jejunum after presenting with a history of anorexia and constipation for several weeks.
H. Avci +6 more
doaj +1 more source