Results 51 to 60 of about 39,976 (222)

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facility

Gülhane Tıp Dergisi
Aims: Clinicopathological features of bone and soft tissue tumors/tumor-like lesions have been shown to vary geographically. This study aims to analyze the clinicopathological features of bone and soft tissue lesions in Ilorin, including both neoplastic ...
Mumini Wemimo Rasheed, Uchechukwu Brian Eziagu, Adebayo Ayoade Adekunle, Najeem Adedamola Idowu, Ismail Salisu, Abdullahi Abba Habib, Enoch Abiodun Afolayan   +6 more
doaj   +1 more source

STUDIES ON OCCURRENCE AND SURGICAL MANAGEMENT OF OCULAR FIBROSARCOMA IN BUFFALOES [PDF]

Exploratory Animal and Medical Research
Medical records of past eight years (2015-23) were investigated to study the occurrence and surgical management of ocular growths in buffaloes. The overall occurrence of ocular fibro sarcoma was found to be 0.8% (15/1753). The buffaloes were of 21 to 49
Kiranjeet Singh
doaj   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Evaluating Fine Needle Aspiration Cytology for Diagnostics of Soft Tissue and Bone Tumours

Cytopathology, EarlyView.
Systematic comparison of needle aspiration cytology and histopathology for 503 tumours in soft tissue and bone showed high concordance (positive predictive value 94%–100%, negative predictive value 83%–89%). In this original study, the authors show that FNAC is a safe and non‐invasive method for diagnosing suspected sarcomas, with the main objective to
Amanda Husu, Sandra Wessman, Karin Wallander, Felix Haglund de Flon   +3 more
wiley   +1 more source

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

Lymphocystis Disease in Endemic Aotearoa New Zealand Bully (Gobiomorphus cotidianus)

Journal of Fish Diseases, EarlyView.
ABSTRACT We detected lymphocystis disease virus (LCDV) for the first time in an Aotearoa New Zealand freshwater environment, from an individual common bully, toitoi, Gobiomorphus cotidianus (Eleotridae). Dinah's bully, Gobiomorphus dinae, and Kaharore bully, Gobiomorphus mataraerore, also exhibited gross nodular lesions on the fins but were not sampled.
Kate S. Hutson, Karthiga Kumanan, Anne Rolton, Emily C. Giles, Joy A. Becker, Maeve Ballantyne, Tim Hewison, Georgia S. Steel, Joshua Wardle, Ashley Webby, Bram T. M. Mulling   +10 more
wiley   +1 more source

CT‐Based Radiomic Features Predict Cervical Lymph Node Metastasis in Dogs With Oral Malignancy: A Machine Learning Study Using Leave‐One‐Patient‐Out Cross‐Validation

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Accurate preoperative identification of cervical lymph node (LN) metastasis is essential for staging and treatment planning in dogs with oral malignancy, yet conventional imaging offers limited diagnostic sensitivity. This retrospective study evaluated whether CT‐derived radiomic features, combined with machine learning classifiers, could ...
Christopher J. Pinard, Andrew Lagree, Ryan Appleby, Michelle Oblak, Kuan‐Chuen Wu, William T. Tran   +5 more
wiley   +1 more source

Primary renal fibrosarcoma: A rare case report and review of literature

Indian Journal of Pathology and Microbiology, 2008
Primary renal fibrosarcoma is a rare tumor. We describe a case of primary renal fibrosarcoma in a 54-year-old male who presented with abdominal lump and intermittent hematuria.
Agarwal Kiran, Singh Smita, Pathania O
doaj  

Immunohistochemical Characterisation of Mismatch Repair Proteins in Feline Cancers: A Pilot Study Using Validated Cross‐Reactive Antibodies

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT DNA mismatch repair (MMR) deficiency is a clinically important biomarker in human oncology, yet its relevance in feline neoplasia remains poorly understood due to limited characterisation and the absence of validated reagents. In this study, we established a practical immunohistochemistry (IHC) approach for evaluating feline MMR proteins by ...
Shoma Nishibori, Masashi Sakurai, Yumiko Kagawa, Kazuo Nishigaki, Takayuki Nakagawa, Sakuya Inanaga, Masaya Igase, Takuya Mizuno   +7 more
wiley   +1 more source