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Breast Journal, 2020 Fibrosarcomatous transformation of dermatofibrosarcoma protuberans (DFSP) is a rare variant with higher risk of recurrence and metastasis, and no known associations with breast implants. We report a rare case of fibrosarcomatous dermatofibrosarcoma protuberans arising at the site of breast implant in a 33-year-old patient followed by brief discussion ...
Koorosh Haghayeghi, David Edmonson
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JDDG - Journal of the German Society of Dermatology, 2023
Zhen Cai, Zhiyuan Jiang, Qingqing Li
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Zhen Cai, Zhiyuan Jiang, Qingqing Li
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Preoperative Risk Factors for Fibrosarcomatous Transformation in Dermatofibrosarcoma Protuberans
Anticancer Research, 2021Dermat of ibrosarcoma protuberans (DFSP) is a soft-tissue sarcoma with a high risk of local recurrence, though typically never metastasizes. DFSP can transform into high-grade fibrosarcoma (DFSP-FS), which has a risk of metastasis. Currently, treatment for DFSP includes Moh's micrographic surgery (MMS); however, this is not recommended for DFSP-FS ...
Katherine E, Mallett +8 more
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Journal of the American Academy of Dermatology, 2015
Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade cutaneous malignancy that sometimes transforms into a high-grade fibrosarcomatous variant (DFSP-FS). Limited data compare clinical features and biological behavior of these 2 entities.We sought to compare clinical features and biological behavior of DFSP and DFSP-FS.This was a retrospective ...
Christine M. Lohse +2 more
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Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade cutaneous malignancy that sometimes transforms into a high-grade fibrosarcomatous variant (DFSP-FS). Limited data compare clinical features and biological behavior of these 2 entities.We sought to compare clinical features and biological behavior of DFSP and DFSP-FS.This was a retrospective ...
Christine M. Lohse +2 more
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Fibrosarcomatous transformation in dermatofibrosarcoma protuberans of the breast—A case report
Journal of Clinical Ultrasound, 2009AbstractDermatofibrosarcoma protuberans (DFSP) is a rare cutaneous malignant tumor that usually occurs in the trunk, extremities, head, and neck but very rarely in the breast. Fibrosarcomatous transformation of DFSP is even rarer, with a higher risk of distant metastasis and poorer prognosis than DFSP.
Joo-Heon Kim +2 more
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Dermatofibrosarcoma protuberans: the diagnosis of high-grade fibrosarcomatous transformation
Skeletal Radiology, 2020Dermatofibrosarcoma protuberans (DFSP) is an intermediate-grade tumour which may undergo fibrosarcomatous transformation to a high-grade sarcoma (DFSP-FST). DFSP-FST requires wide local resection, and therefore, pre-operative identification is important.
Paul, Choong +3 more
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Human Cell, 2023
Dermatofibrosarcoma protuberans (DFSP) is a superficial low-grade sarcoma, genetically characterized by a fusion gene in collagen type I α (COL1A1) gene and platelet-derived growth factor subunit β (PDGFB). DFSP is locally aggressive and does not typically metastasize.
Tadashi Kondo, Taro Akiyama, Yooksil Sin
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Dermatofibrosarcoma protuberans (DFSP) is a superficial low-grade sarcoma, genetically characterized by a fusion gene in collagen type I α (COL1A1) gene and platelet-derived growth factor subunit β (PDGFB). DFSP is locally aggressive and does not typically metastasize.
Tadashi Kondo, Taro Akiyama, Yooksil Sin
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The Prognostic Significance of Fibrosarcomatous Transformation in Dermatofibrosarcoma Protuberans
The American Journal of Surgical Pathology, 2006Dermatofibrosarcoma protuberans (DFSP) is a superficial tumor characterized by high rates of local recurrence and a small risk of metastasis. Fibrosarcomatous (FS) areas rarely arise in DFSP, and considerable controversy exists as to whether these tumors have a higher risk of metastasis than the typical DFSP. The aim of this study was to reappraise the
Jared J, Abbott +2 more
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Long-term results of treatment of advanced dermatofibrosarcoma protuberans (DFSP) with imatinib mesylate – The impact of fibrosarcomatous transformation [PDF]
European Journal of Surgical Oncology, 2017 Dermatofibrosarcoma protuberans (DFSP) is rare, infiltrating dermal neoplasm, characterized by indolent growth and low probability of metastases. The first effective systemic therapy in DFSP introduced into clinical practice was imatinib, demonstrating high activity in advanced cases.
Piotr Rutkowski, M Debiec-Rychter
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