Results 131 to 140 of about 1,564,648 (152)

Management of dermatofibrosarcoma protuberans with fibrosarcomatous transformation: an evidence-based review of the literature

Journal of the European Academy of Dermatology and Venereology, 2011
AbstractFibrosarcomatous transformation represents a rare event in dermatofibrosarcoma protuberans (DFSP) with unpredictable biological behaviour. No guidelines for the adequate treatment of patients with this rare neoplasm have been published. Herein, we present a comprehensive review of the literature comprising 157 patients with transformed DFSP ...
Joerg Wenzel, Thomas Bieber, C -M Wendtner   +2 more
exaly   +3 more sources

Fibrosarcomatous Transformation of a Dermatofibrosarcoma Protuberans During Pregnancy

Dermatologic Surgery, 2015
Yevgeniya Byekova, Gerardo Marrazzo, Ryan Thorpe, Joseph Susa, Stan Taylor   +4 more
exaly   +2 more sources

Dermatofibrosarcoma protuberans with fibrosarcomatous transformation: a case report.

Ceskoslovenska patologie, 2020
Dermatofibrosarcoma protuberans is a quite rare local aggressive tumor of dermis and subcutis, revealing characteristic morphology and chromosomal translocation (17; 22)(q21;q13) with gene fusion COL1A1-PDGFB. The tumour almost never metastasizes and complete excision signs an excellent prognosis.
Jan, Hrudka, Martin, Charvát, Petr, Grossmann, Zdeněk, Kinkor   +3 more
openaire   +1 more source

Fibrosarcomatous Transformation in Dermatofibrosarcoma Protuberans of the Male Breast and its Association with Magnetic Resonance Imaging and Immunohistopathologic Features

Current Medical Imaging
Background: Dermatofibrosarcoma Protuberans (DFSP) is a rare soft tissue sarcoma, accounting for approximately 1% of all tumors; however, DFSP of the breast is extremely rare. Moreover, DFSP generally has a low malignant potential and is characterized by a high rate of local recurrence along with a small but definite risk of metastasis.
Eun Jung Choi, Sang Yull Kang, Kyu Yun Jang   +2 more
exaly   +3 more sources

Multi-omic profiling and real time ex vivo modelling of imatinib-resistant dermatofibrosarcoma protuberans with fibrosarcomatous transformation

Human Cell, 2023
Dermatofibrosarcoma protuberans (DFSP) is a rare and indolent cutaneous sarcoma, with the risk of aggressive fibro-sarcomatous transformation. Limited effective options are available for un-resectable or metastatic DFSP beyond targeting the oncogenic PDGF pathway with imatinib therapy.
Jason Yongsheng Chan, Elizabeth Chun Yong Lee, Zhimei Li, Jing Yi Lee, Abner Herbert Lim, Eileen Poon   +5 more
openaire   +2 more sources

Dermatofibrosarcoma protuberans with fibrosarcomatous transformation: our experience, molecular evaluation of selected cases, and short literature review

International Journal of Dermatology, 2019
AbstractDermatofibrosarcoma protuberans with fibrosarcomatous transformation (DFSP‐FS) is a higher grade tumor arising from dermatofibrosarcoma protuberans (DFSP). Recent literature highlights its impact on recurrence rates, metastatic rates, and survival.
Karen Elizabeth Schoedel, Liurka V Lopez, Svetlana Yatsenko   +2 more
exaly   +3 more sources

[An uncommon malignancy of the breast: dermatofibrosarcoma protuberans with fibrosarcomatous transformation (DFSP-FS)].

Magyar sebeszet, 2009
Dermatofibrosarcoma protuberans (DFSP) is a morphologically distinct dermal/subcutaneous fibrohystiocytic neoplasm seen mainly on the trunk and the proximal extremities, which generally is regarded as a low-grade or "borderline" neoplasm. Dermatofibrosarcoma protuberans is characterized clinically by locally aggressive growth and a high rate of local ...
György, Ledniczky, Gábor, Bognár, Csaba, Diczházi, Bíborka, Bereczky, Loránd, Barabás, Pál, Ondrejka   +5 more
openaire   +2 more sources

Digital Spatial Profiling Demonstrates Differences Between Fibrosarcomatous Transformation of Dermatofibrosarcoma Protuberans and Its Conventional Counterparts

Modern Pathology
Dermatofibrosarcoma protuberans (DFSP) is a neoplasm of the dermis with a tendency for aggressive local growth and recurrence. A minority of DFSP cases may transform into higher-grade sarcoma (fibrosarcomatous transformation [FST]) (DFSP-FST), which is associated with more aggressive behavior and risk of metastasis. The histologic diagnosis of DFSP-FST
Ata S Moshiri, Robert W Ricciotti, Shreeram Akilesh   +2 more
exaly   +3 more sources

Dermatofibrosarcoma protuberans with fibrosarcomatous areas. Molecular abnormalities of the p53 pathway in fibrosarcomatous transformation of dermatofibrosarcoma protuberans.

Virchows Archiv : an international journal of pathology, 1998
Fibrosarcomatous (FS) change in a rare, but well-known phenomenon encountered in dermatofibrosarcoma protuberans (DFSP), and an increased chance in an adverse outcome has been suggested in patients with DFSP having FS areas (DFSP-FS). As altered p53 pathway has been suggested as having a potential role in tumour progression, we analysed the p53 gene ...
M, Hisaoka, S, Okamoto, Y, Morimitsu, S, Tsuji, H, Hashimoto   +4 more
openaire   +1 more source

A novel MAP3K7CL‐ERG fusion in a molecularly confirmed case of dermatofibrosarcoma protuberans with fibrosarcomatous transformation

Journal of Cutaneous Pathology, 2019
Dermatofibrosarcoma protuberans (DFSP) is a translocation‐associated, low‐grade sarcoma with fibroblastic differentiation. It is the most common superficial sarcoma, almost exclusively arising within the dermis. In a minority of cases, there is a transition from the conventional morphology to a fibrosarcomatous pattern, known as a fibrosarcomatous DFSP
Nolan Maloney, Julia A. Bridge, Francine de Abreu, Penelope Korkolopoulou, Stratigoula Sakellariou, Konstantinos Linos   +5 more
openaire   +2 more sources