Results 11 to 20 of about 1,024,087 (311)

Inflammasomes and Fibrosis [PDF]

open access: yesFrontiers in Immunology, 2021
Fibrosis is the final common pathway of inflammatory diseases in various organs. The inflammasomes play an important role in the progression of fibrosis as innate immune receptors. There are four main members of the inflammasomes, such as NOD-like receptor protein 1 (NLRP1), NOD-like receptor protein 3 (NLRP3), NOD-like receptor C4 (NLRC4), and absent ...
Wen-Juan Zhang   +5 more
openaire   +3 more sources

Elexacaftor/tezacaftor/ivacaftor as rescue therapy in a patient with the cystic fibrosis genotype F508DEL/G1244E

open access: yesClinical Case Reports, 2021
Elexacaftor/tezacaftor/ivacaftor (ETI) is a cystic fibrosis (CF) transmembrane regulator (CFTR) modulator. It is known to be efficacious in stable patients with severe pneumopathy, but there are few data concerning its effectiveness during acute ...
Donatello Salvatore   +4 more
doaj   +1 more source

Paraquat ingestion in an adult with cystic fibrosis (CF): Diagnostic and management dilemmas

open access: yesRespirology Case Reports, 2023
N,N'‐dimethyl‐4,4'bipyridinium dichloride (Paraquat) is a potent herbicide used widely in agriculture. We report the effects of an ingestion of paraquat by a 28 year old male with cystic fibrosis and the diagnostic and management challenges this posed in
Ieuan E. S. Evans   +8 more
doaj   +1 more source

Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity [PDF]

open access: yes, 2011
Lung epithelial cells exhibit a high degree of plasticity. Alterations to lung epithelial cell function are critically involved in several chronic lung diseases such as pulmonary fibrosis.
Königshoff, M.   +2 more
core   +1 more source

MicroRNAs in fibrosis: opportunities and challenges [PDF]

open access: yes, 2016
MicroRNAs (miRNAs) are small, non-coding RNAs that mediate mRNA cleavage, translational repression or mRNA destabilisation and are around 22-25 nucleotides in length via partial complementary binding to the 3' untranslated region in target transcripts ...
O'Reilly, Steven, Steven O’Reilly
core   +1 more source

Guía de Práctica Clínica para el manejo nutricional de personas con Fibrosis Quística (GPC-FQ)

open access: yesRevista Española de Nutrición Humana y Dietética, 2017
La fibrosis quística (FQ) es una enfermedad multiorgánica, hereditaria, autosómica y recesiva cuyos problemas más frecuentes están relacionados con las alteraciones de los pulmones y del páncreas exocrino.
María Garriga   +7 more
doaj   +1 more source

Recombinant truncated latency-associated peptide alleviates liver fibrosis in vitro and in vivo via inhibition of TGF-β/Smad pathway

open access: yesMolecular Medicine, 2022
Background Liver fibrosis is a progressive liver injury response. Transforming growth factor β1 (TGF-β1) is oversecreted during liver fibrosis and promotes the development of liver fibrosis.
Xudong Song   +10 more
doaj   +1 more source

How do adults with cystic fibrosis cope following a diagnosis of diabetes? [PDF]

open access: yes, 2008
The official published version of the article can be obtained from the link below.Aim. This paper is a report of a study examining the experience of adults with cystic fibrosis in adapting to the diagnosis of diabetes, a second chronic illness ...
Reynolds, F, Collins, S
core   +1 more source

Standards of care for CFTR variant-specific therapy (including modulators) for people with cystic fibrosis [PDF]

open access: yes, 2023
Cystic fibrosis; Guidelines; Variant-specific therapyFibrosis quística; Pautas; Terapia variante específicaFibrosi quística; Pautes; Teràpia variant específicaCystic fibrosis (CF) has entered the era of variant-specific therapy, tailored to the genetic ...
Southern, Kevin   +6 more
core   +1 more source

Retroperitoneal fibrosis [PDF]

open access: yesVascular Medicine, 2014
Retroperitoneal fibrosis (RPF) is a rare disease that is marked by systemic inflammation and the development of a periaortic fibroinflammatory mass. The fibroinflammatory infiltration can encase the abdominal aorta, ureters, and other abdominal organs. The clinical presentation often includes constitutional symptoms, abdominal pain, and signs of renal ...
Martha, Tzou   +2 more
openaire   +2 more sources

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