Results 31 to 40 of about 952,925 (309)

Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers [PDF]

, 2012
Background: Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly attributable to co-infection with hepatitis B or C. The impact of other risk factors, including prolonged exposure to combined antiretroviral therapy (cART ...
Annika Vermehren, Stefan Zeuzem, Gute, Peter, Poynard, Thierry, Friedrich-Rust, Mireen, Vermehren, Johannes, Peter Gute, Sarrazin, Christoph, Christoph Sarrazin, Amina Carlebach, Johannes Vermehren, Carlebach, Amina, Axel Mueller, Vermehren, Annika, Lutz, Thomas, Forestier, Nicole, Herrmann, Eva, Thomas Lutz, Thierry Poynard, Mireen Friedrich-Rust, Knecht, Gaby, Wolf Peter Hofmann, Hofmann, Wolf-Peter, Eva Herrmann, Nicole Forestier, Gaby Knecht, Mueller, Axel, Zeuzem, Stefan   +27 more
core   +2 more sources

The changing epidemiology of Burkholderia species infection at an adult cystic fibrosis centre [PDF]

, 2008
Background: This study reviews the impact of changing infection control practices at the Manchester Adult Cystic Fibrosis Centre (MACFC) upon the epidemiology of Burkholderia species infections.Methods: We reviewed strain and genomovar typing of all ...
Doherty, Catherine J., Govan, John R., Dodd, Mary E., Webb, A. K., Jones, Andrew M., France, Megan W.   +5 more
core   +1 more source

Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset [PDF]

, 2011
Acute periods of pulmonary exacerbation are the single most important cause of morbidity in cystic fibrosis patients, and may be associated with a loss of lung function.
Matt W Johnson, Rogers, Geraint B., Carroll, Mary P., Carroll, Mary P, Mayer-Hamblett, Nicole, Geraint B Rogers, Jürgen Schwarze, Kenneth D Bruce, Mary P Carroll, Johnson, Matt W, Hoffman, Lucas R, Nicole Mayer-Hamblett, Johnson, Matt W., Rogers, Geraint B, Schwarze, Juergen, Schwarze, Jürgen, Bruce, Kenneth D., Lucas R Hoffman, Hoffman, Lucas R., Bruce, Kenneth D   +19 more
core   +1 more source

Upregulation of a CFTR mRNA isoform has therapeutic potential for the treatment of 3′ CFTR PTC variants

Molecular Therapy: Nucleic Acids
Nonsense or premature termination codon (PTC) variants of the CFTR gene are pathogenic and found in ∼10% of North American people with cystic fibrosis.
Normand E. Allaire, Matthew S. Armstrong, Jae Seok Yoon, Mercy C. Walker, Priyanka Bhatt, Jan M. Harrington, Yi Cheng, Eric I. Wong, John E. Mahoney, Hillary C. Valley, Caitlin M. Macadino, Hermann J. Bihler, Andrey Y. Sivachenko, Calvin U. Cotton, John P. Carulli, Martin Mense   +15 more
doaj   +1 more source

Elevated sweat chloride test: is it always cystic fibrosis?

Italian Journal of Pediatrics, 2021
Background The sweat chloride test (ST) is the gold standard for cystic fibrosis (CF) diagnosis in symptomatic patients, within the newborn screening and in the follow-up of CF patients during molecular therapies.
C. Cimbalo, A. Tosco, V. Terlizzi, A. Sepe, A. Castaldo, L. Salvadori, V. Raia   +6 more
doaj   +1 more source

Diabetic fibrosis

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2021
Diabetes-associated morbidity and mortality is predominantly due to complications of the disease that may cause debilitating conditions, such as heart and renal failure, hepatic insufficiency, retinopathy or peripheral neuropathy. Fibrosis, the excessive and inappropriate deposition of extracellular matrix in various tissues, is commonly found in ...
Izabela, Tuleta, Nikolaos G, Frangogiannis   +1 more
openaire   +3 more sources

Absence of a gender gap in survival. An analysis of the Italian registry for cystic fibrosis in the paediatric age.

, 2011
BACKGROUND: The existence of gender-related differences since childhood in survival of cystic fibrosis (CF) patients has been recently challenged.
Bossi A, Italian Registry for Cystic Fibrosis Collaborative Group, ASSAEL, BAROUKHMAURICE, Viviani L   +3 more
core   +1 more source

Immunisation in the current management of cystic fibrosis patients. [PDF]

, 2005
Although no special recommendations exist, clearly patients with cystic fibrosis (CF) can benefit from immunisation. We reviewed the literature regarding vaccination in CF and other chronic diseases.
Ciofu, Oana, Dab, Isi, D\uf6ring, Gerd, Bush, Andrew, European Cystic Fibrosis Society (ECFS) Vaccination Group, Adam, Georgios, Lang, Alo\uefs B., Döring, Gerd, Malfroot, Anne, Lang, Aloïs B., Lang, Aloïs B, Knoop, Christiane, Van Damme, Pierre   +12 more
core   +1 more source

REAL‐world clinical effectiveness of ivacaftor therapy in the first 24 months in two infants with cystic fibrosis and different gating mutations—A case report

Clinical Case Reports, 2022
This study summarizes efficacy of ivacaftor treatment in 2 infants in a real‐world setting. A distinct decline of sweat chloride and lung clearance index plus increase in fecal elastase was seen. The results underline the early and sustainable effect and
Teresa Fuchs, Dorothea Appelt, Katharina Niedermayr, Helmut Ellemunter   +3 more
doaj   +1 more source

Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis [PDF]

, 2011
Background The balancing functions of pro/anti-inflammatory mediators of the complex innate responses have been investigated in a variety of experimental inflammatory settings. Annexin-A1 (AnxA1) is one mediator of endogenous anti-inflammation, affording
Amílcar S Damazo, Damazo Amílcar S, Damazo, Amilcar S. [UNESP], Perretti, M, Perretti, Mauro, Oliani, Sonia M. [UNESP], Sampaio André LF, Sampaio, Andre L. F., Cintia MAG Nakata, Damazo, AS, Mauro Perretti, Nakata, Cintia M. A. G., Oliani, Sonia M., Roderick J Flower, Sonia M Oliani, Sampaio, ALF, Damazo, Amilcar S., Oliani, SM, Flower, Roderick J., Oliani Sonia M, Flower, RJ, André LF Sampaio, Flower Roderick J, Perretti Mauro, Nakata Cintia MAG, Nakata, CMAG   +25 more
core   +1 more source