Results 31 to 40 of about 1,024,087 (311)

Virtual Peer Support for People With Cystic Fibrosis and Their Family Members: A Program Evaluation

Journal of Patient Experience, 2020
We sought to evaluate the feasibility, acceptability, and benefits of a virtual one-to-one peer support program for people with cystic fibrosis and their family members through a retrospective program evaluation.
Aimee Jeffrey MSN, Lauren Andracchio MPH, Meg Dvorak LCSW, Paula Lomas MAS, RN, CCRP, Beth Smith MD, Drucy Borowitz MD   +5 more
doaj   +1 more source

Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset [PDF]

, 2011
Acute periods of pulmonary exacerbation are the single most important cause of morbidity in cystic fibrosis patients, and may be associated with a loss of lung function.
Matt W Johnson, Rogers, Geraint B., Carroll, Mary P., Carroll, Mary P, Mayer-Hamblett, Nicole, Geraint B Rogers, Jürgen Schwarze, Kenneth D Bruce, Mary P Carroll, Johnson, Matt W, Hoffman, Lucas R, Nicole Mayer-Hamblett, Johnson, Matt W., Rogers, Geraint B, Schwarze, Juergen, Schwarze, Jürgen, Bruce, Kenneth D., Lucas R Hoffman, Hoffman, Lucas R., Bruce, Kenneth D   +19 more
core   +1 more source

Incidence of SARS-CoV-2 in people with cystic fibrosis in Europe between February and June 2020 [PDF]

, 2021
Funding Information: We thank the people with CF, and their families, for consenting to their data being included in the ECFSPR. We thank the centers and individual country representatives for allowing the use of the anonymized patient data.
European Cystic Fibrosis COVID project group, Aleksejeva, Elina, Naehrlich, Lutz   +2 more
core   +1 more source

Serum proteome profiling identifies novel and powerful markers of cystic fibrosis liver disease. [PDF]

, 2013
Cystic Fibrosis associated liver disease (CFLD) develops in approximately 30% of CF patients. However, routine sensitive diagnostic tools for CFLD are lacking. Within this study, we aimed to identify new experimental biomarkers for the detection of CFLD.
Richard Schulz, Martin Roderfeld, Roderfeld, Martin, Lisa Hage, Timo Rath (389419), Reinhart Zachoval (76840), Katrin Menendez Menendez (389422), Lutz Naehrlich (389423), Martin Roderfeld (389425), Hage, Lisa, Marion Kügler, Richard Schulz (389424), Marion Kügler (389421), Elke Roeb (389426), Timo Rath, Kügler, Marion, Rath, Timo, Roeb, Elke, Katrin Menendez Menendez, Reinhart Zachoval, Elke Roeb, Menendez Menendez, Katrin, Lutz Naehrlich, Lisa Hage (389420), Zachoval, Reinhart, Naehrlich, Lutz, Schulz, Richard, Roeb Elke, Rath Timo, Hage Lisa, Schulz Richard, Kügler Marion, Zachoval Reinhart, Roderfeld Martin, Menendez Menendez Katrin, Naehrlich Lutz   +35 more
core   +1 more source

Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype phenotype correlations [PDF]

, 1996
We have generated a mouse carrying the human G551D mutation in the cystic fibrosis transmembrane conductance regulator gene (CFTR) by a one-step gene targeting procedure, These mutant mice show cystic fibrosis pathology but have a reduced risk of fatal ...
Wainwright, Brandon J., Smith, S. N., Alton, Ewfw, Lamb, D., Lunn, D. P., Porteous, D. J., Alton, Eric W.F.W., Dorin, Julia R., Porteous, David J., Delaney, S. J., Farley, Ray, Dorin, J. R., Lunn, Dominic P., Lovelock, P. K., Delaney, Stephen J., Lovelock, Paul K., Smith, Stephen N., Wainwright, B. J., Thomson, Scott A., Hume, D. A., Farley, R., Thomson, S. A., Hume, David A., Lamb, David   +23 more
core   +1 more source

Upregulation of a CFTR mRNA isoform has therapeutic potential for the treatment of 3′ CFTR PTC variants

Molecular Therapy: Nucleic Acids
Nonsense or premature termination codon (PTC) variants of the CFTR gene are pathogenic and found in ∼10% of North American people with cystic fibrosis.
Normand E. Allaire, Matthew S. Armstrong, Jae Seok Yoon, Mercy C. Walker, Priyanka Bhatt, Jan M. Harrington, Yi Cheng, Eric I. Wong, John E. Mahoney, Hillary C. Valley, Caitlin M. Macadino, Hermann J. Bihler, Andrey Y. Sivachenko, Calvin U. Cotton, John P. Carulli, Martin Mense   +15 more
doaj   +1 more source

Elevated sweat chloride test: is it always cystic fibrosis?

Italian Journal of Pediatrics, 2021
Background The sweat chloride test (ST) is the gold standard for cystic fibrosis (CF) diagnosis in symptomatic patients, within the newborn screening and in the follow-up of CF patients during molecular therapies.
C. Cimbalo, A. Tosco, V. Terlizzi, A. Sepe, A. Castaldo, L. Salvadori, V. Raia   +6 more
doaj   +1 more source

Diabetic fibrosis

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2021
Diabetes-associated morbidity and mortality is predominantly due to complications of the disease that may cause debilitating conditions, such as heart and renal failure, hepatic insufficiency, retinopathy or peripheral neuropathy. Fibrosis, the excessive and inappropriate deposition of extracellular matrix in various tissues, is commonly found in ...
Izabela, Tuleta, Nikolaos G, Frangogiannis   +1 more
openaire   +3 more sources

Magnetic resonance imaging as a non-invasive tool to investigate pulmonary and renal fibrosis in small rodents : method and readout validation, animal model optimization, and substance testing [PDF]

, 2015
Pulmonary fibrosis, an end result of various types of lung damage including interstitial pneumonia and respiratory bronchiolitis (Gross and Hunninghake, 2001; Katzenstein and Myers, 1998; Lazenby et al., 1990) is a lethal disease characterized by ...
Egger, Christine
core   +1 more source

REAL‐world clinical effectiveness of ivacaftor therapy in the first 24 months in two infants with cystic fibrosis and different gating mutations—A case report

Clinical Case Reports, 2022
This study summarizes efficacy of ivacaftor treatment in 2 infants in a real‐world setting. A distinct decline of sweat chloride and lung clearance index plus increase in fecal elastase was seen. The results underline the early and sustainable effect and
Teresa Fuchs, Dorothea Appelt, Katharina Niedermayr, Helmut Ellemunter   +3 more
doaj   +1 more source