Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis [PDF]
Background The balancing functions of pro/anti-inflammatory mediators of the complex innate responses have been investigated in a variety of experimental inflammatory settings. Annexin-A1 (AnxA1) is one mediator of endogenous anti-inflammation, affording
Amílcar S Damazo +25 more
core +1 more source
Malignancies in patients with cystic fibrosis: a case series
Background Previous reports have shown an increased number of colorectal cancers in patients with cystic fibrosis. We assessed the database of our cystic fibrosis center to identify patients with all kinds of cancer retrospectively. All patients visiting
Dorothea Appelt +3 more
doaj +1 more source
Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis [PDF]
Background: FibroTest (FT) is the most frequently used serum fibrosis marker and consists of an algorithm of five fibrosis markers (alfa2-macroglobulin, apolipoproteinA1, haptoglobin, GGT, bilirubin). The Enhanced Liver Fibrosis (ELF) test consists of an
Julie Parkes +12 more
core +2 more sources
BACKGROUND: The existence of gender-related differences since childhood in survival of cystic fibrosis (CF) patients has been recently challenged.
Bossi A +3 more
core +2 more sources
Background: Cystic fibrosis (CF) patients require regular airway clearance therapy (ACT). The aim of this study was to evaluate homecare therapeutic effects of a new ACT (Simeox®) added to the optimal standard of care, including home chest physiotherapy,
Dorota Sands +8 more
doaj +1 more source
Non-invasive ventilation and clinical outcomes in cystic fibrosis: Findings from the UK CF registry [PDF]
Background: Non-invasive ventilation (NIV) for respiratory failure and airway clearance is an established intervention in cystic fibrosis (CF), but its therapeutic benefit on lung function and survival remains under-investigated. Methods: Using data from
Bilton, D +5 more
core +1 more source
Research progress on multiple cell death pathways of podocytes in diabetic kidney disease
Diabetic kidney disease (DKD) is the main cause of end-stage renal disease, and its clinical manifestations are progressive proteinuria, decreased glomerular filtration rate, and renal failure. The injury and death of glomerular podocytes are the keys to
Can Yang +7 more
doaj +1 more source
Clinical complications in children with false-negative results in cystic fibrosis newborn screening
Objective: To present signs and symptoms and clinical course in cystic fibrosis patients with false-negative newborn screening (CF NBS). Materials and methods: All children presented in this paper were covered by CF NBS.
Katarzyna Zybert +5 more
doaj +1 more source
Incidence and risk factors of cancer in individuals with cystic fibrosis in the UK; a case-control study. [PDF]
To assess cancer incidence in the UK cystic fibrosis (CF) population and determine the associated risk factors, we undertook a nested case-control study of patients with CF, registered with the UK CF Registry.
Mentzakis, Emmanouil +15 more
core +1 more source
Prokaryotic expression, purification and evaluation of anti-cardiac fibrosis activity of recombinant TGF-β latency associated peptide [PDF]
Background Cardiac fibrosis refers to the abnormal accumulation of extracellular matrix in the heart, which leads to the formation of cardiac scars. It causes systolic and diastolic dysfunction, and ultimately leads to cardiac dysfunction and arrhythmia.
Xudong Song +6 more
doaj +2 more sources

