Results 1 to 10 of about 22,028 (227)

FUNCIÓN PULMONAR EN FIBROSIS QUÍSTICA

open access: yesNeumología Pediátrica, 2022
La fibrosis quística (FQ) es una enfermedad hereditaria autosómica recesiva, causada por la mutación del gen que codifica la proteína CFTR (cystic fibrosis transmembrane conductance regulator), afecta varios órganos, pero la enfermedad pulmonar es la ...
Hortensia Barrientos
doaj   +2 more sources

Mitochondrial proteomics reveals reductive metabolism dependent on glutamine in fibroblasts of idiopathic pulmonary fibrosis under hypoxia [PDF]

open access: yesScientific Reports
Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), is a chronic disease characterized not only by a transcriptionally active signature associated with hypoxia but also by feedback loops that may underlie disease progression.
Yair Romero   +19 more
doaj   +2 more sources

Eosinophilic cytokines and small airway dysfunction in women with COPD: correlation with exposure to biomass smoke versus tobacco smoking [PDF]

open access: yesIJTLD Open
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease characterised by progressive airflow obstruction. Tobacco smoking is the leading cause of COPD (COPD-TS); however, chronic exposure to biomass smoke (COPD-BS) is ...
R. Robles-Hernández   +7 more
doaj   +2 more sources

Absence of HDAC3 by Matrix Stiffness Promotes Chromatin Remodeling and Fibroblast Activation in Idiopathic Pulmonary Fibrosis

open access: yesCells, 2023
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease characterized by progressive and irreversible lung scarring associated with persistent activation of fibroblasts.
Fernanda Toscano-Marquez   +3 more
doaj   +1 more source

Short-Term Exposure to Wood Smoke Increases the Expression of Pro-Inflammatory Cytokines, Gelatinases, and TIMPs in Guinea Pigs

open access: yesToxics, 2021
Exposure to air pollutants in wildfire smoke and indoor pollution causes lung diseases. Short-term exposure to wood smoke (WS) is partially known to alter the expression of human matrix metalloproteinases (MMPs), inflammatory cytokines, and tissue ...
Carlos Ramos   +6 more
doaj   +1 more source

Síndrome combinado de fibrosis pulmonar y enfisema: albores del tratamiento antifibrótico en el Paraguay

open access: yesMemorias del Instituto de Investigaciones en Ciencias de la Salud, 2022
La concomitancia de fibrosis pulmonar en regiones inferiores del pulmón y enfisema en lóbulos superiores caracterizan a una entidad poco frecuente denominada síndrome combinado de fibrosis pulmonar y enfisema, que usualmente se asocia a alta carga de ...
Domingo Pérez-Bejarano
doaj   +1 more source

Pharmacokinetic evaluation of two pirfenidone formulations in patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis

open access: yesHeliyon, 2020
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease characterized by an abnormal activation of lung epithelium and fibroblasts, as well as an excessive accumulation of extracellular matrix.
Lina Marcela Barranco-Garduño   +10 more
doaj   +1 more source

Effect of Hypoxia in the Transcriptomic Profile of Lung Fibroblasts from Idiopathic Pulmonary Fibrosis

open access: yesCells, 2022
Idiopathic pulmonary fibrosis (IPF) is an aging-associated disease characterized by exacerbated extracellular matrix deposition that disrupts oxygen exchange.
Yair Romero   +17 more
doaj   +1 more source

Toxicidad pulmonar secundaria a bleomicina. Reporte de caso

open access: yesRespirar, 2023
La toxicidad pulmonar por antineoplásicos es muy variable dependiente del grupo farmacológico; la bleomicina es uno de los medicamentos en los que se ha reportado este evento.
Luis Eduardo Ramirez Bejarano   +3 more
doaj   +1 more source

Fibrosis quística: patogenia bacteriana y moduladores del CFTR (regulador de conductancia transmembranal de la fibrosis quística)

open access: yesBoletín Médico del Hospital Infantil de México, 2022
La fibrosis quística es una enfermedad hereditaria autosómica recesiva que se origina por mutaciones en el gen regulador de conductancia transmembranal de la fibrosis quística (CFTR, cystic fibrosis transmembrane conductance regulator).
Silvia Y. Vargas-Roldán   +5 more
doaj   +1 more source

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