Results 11 to 20 of about 1,838 (171)

Physiological and pathophysiological roles of the KCNK3 potassium channel in the pulmonary circulation and the heart

The Journal of Physiology, Volume 601, Issue 17, Page 3717-3737, 1 September 2023., 2023
Abstract figure legend Potassium channel subfamily K member 3 (KCNK3) is functionally expressed in pulmonary vascular and cardiac cells. KCNK3 loss of function and expression leads to pulmonary arterial hypertension (PAH) and right ventricular failure (RVF).
Anaïs Saint‐Martin Willer, Joana Santos‐Gomes, Rui Adão, Carmen Brás‐Silva, Mélanie Eyries, Francisco Pérez‐Vizcaino, Véronique Capuano, David Montani, Fabrice Antigny   +8 more
wiley   +1 more source

RhoA/ROCK2 signalling is enhanced by PDGF‐AA in fibro‐adipogenic progenitor cells: implications for Duchenne muscular dystrophy

Journal of Cachexia, Sarcopenia and Muscle, Volume 13, Issue 2, Page 1373-1384, April 2022., 2022
Abstract Background The lack of dystrophin expression in Duchenne muscular dystrophy (DMD) induces muscle fibre and replacement by fibro‐adipose tissue. Although the role of some growth factors in the process of fibrogenesis has been studied, pathways activated by PDGF‐AA have not been described so far.
Esther Fernández‐Simón, Xavier Suárez‐Calvet, Ana Carrasco‐Rozas, Patricia Piñol‐Jurado, Susana López‐Fernández, Gemma Pons, Joan Josep Bech Serra, Carolina de la Torre, Noemí de Luna, Eduard Gallardo, Jordi Díaz‐Manera   +10 more
wiley   +1 more source

Matrix Metalloproteinases and Stress Hormones in Lung Cancer Progression

Journal of Oncology, Volume 2022, Issue 1, 2022., 2022
Several matrix metalloproteinases (MMPs) and psychological stress are associated with poor cancer prognosis. The current work goal was to determine MMPs’ and stress hormones’ blood concentrations from lung adenocarcinoma (LAC) patients. Patients were divided into the following groups: tobacco smokers (TS), wood smoke‐exposed (W), passive smokers (PS ...
Georgina Gonzalez-Avila, Bettina Sommer, A. Armando Garcia-Hernandez, Carlos Ramos, Javier Delgado, Lilia Vazquez, Rosa A. Gonzalez, Cuauhtemoc Sandoval, Edgar Flores-Soto, Haigang Wu   +9 more
wiley   +1 more source

Fibrosis Pulmonar Idiopática

Diagnóstico, 2020
Las enfermedades pulmonares intersticiales difusas (EPID) son desórdenes no neoplásicos que resultan en el daño del parénquima pulmonar con una variedad de patrones que van desde inflamación a fibrosis(1). La clasificación tradicional se enfoca primordialmente en las asociaciones conocidas subyacentes que incluyen: a) enfermedades del tejido conjuntivo
Maria Venero-Cáceres, Edwin H. Herrera-Flores, Juan A. Salas-López, Félix K. Llanos-Tejada, Carlos A. Saavedra-Leveau   +4 more
openaire   +2 more sources

Toxicidad pulmonar secundaria a bleomicina. Reporte de caso

Respirar, 2023
La toxicidad pulmonar por antineoplásicos es muy variable dependiente del grupo farmacológico; la bleomicina es uno de los medicamentos en los que se ha reportado este evento.
Luis Eduardo Ramirez Bejarano, Karen Yuliana Ramírez Iriarte, Luisa Alejandra Maya Caicedo, Wilmer Orlando Aponte Barrios   +3 more
doaj   +1 more source

Fibrosis quística: patogenia bacteriana y moduladores del CFTR (regulador de conductancia transmembranal de la fibrosis quística)

Boletín Médico del Hospital Infantil de México, 2022
La fibrosis quística es una enfermedad hereditaria autosómica recesiva que se origina por mutaciones en el gen regulador de conductancia transmembranal de la fibrosis quística (CFTR, cystic fibrosis transmembrane conductance regulator).
Silvia Y. Vargas-Roldán, José L. Lezana-Fernández, Jorge F. Cerna-Cortés, Santiago Partida-Sánchez, José I. Santos-Preciado, Roberto Rosales-Reyes   +5 more
doaj   +1 more source

Exercise Improves Lung Inflammation, but Not Lung Remodeling and Mechanics in a Model of Bleomycin‐Induced Lung Fibrosis

Oxidative Medicine and Cellular Longevity, Volume 2020, Issue 1, 2020., 2020
Introduction. Moderate aerobic exercise training accelerates the resolution of lung fibrosis in a model of bleomycin‐induced pulmonary fibrosis. However, whether it can inhibit the development of lung fibrosis is unknown. Materials and Methods. C57Bl/6 mice were distributed into four groups: Control (Co), Exercise (Exe), Bleomycin (Bleo), and Bleomycin+
Elias El-Mafarjeh, Gisele Henrique Cardoso Martins, Jessica Jorge Probst, Alana Santos-Dias, Manoel Carneiro Oliveira-Junior, Marcelo Paes de Barros, Luis Vicente Franco de Oliveira, Leandro Damas de Andrade, Renata Kelly da Palma, Renilson Moraes-Ferreira, Deborah de Camargo Hizume-Kunzler, André Luis Lacerda Bachi, Rodolfo P. Vieira, Gr gory Durand   +13 more
wiley   +1 more source

Women with COPD by biomass show different serum profile of adipokines, incretins, and peptide hormones than smokers

Respiratory Research, 2018
Background The main causes of COPD are tobacco smoking (COPD-TS) and biomass smoke exposure (COPD-BS). COPD-TS is known to induce changes in adipokines, incretins, and peptide hormones, frequent biomarkers of inflammation; however, it is unknown if ...
Oliver Pérez-Bautista, Martha Montaño, Rogelio Pérez-Padilla, Joaquín Zúñiga-Ramos, Mariana Camacho-Priego, Tonatiuh Barrientos-Gutiérrez, Ivette Buendía-Roldan, Yadira Velasco-Torres, Carlos Ramos   +8 more
doaj   +1 more source

Fibrosis pulmonar familiar en el síndrome de Hermansky-Pudlak

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2022
La fibrosis pulmonar familiar en el contexto del síndrome de Hermansky-Pudlak es una entidad nosológica poco frecuente y cuyo único enfoque terapéutico definitivo es el trasplante pulmonar en los estadios avanzados.
Domingo Pérez-Bejarano
doaj   +1 more source

Trasplante pulmonar en pacientes con fibrosis pulmonar idiopática [PDF]

Revista chilena de enfermedades respiratorias, 2019
Pulmonary transplantation represents a therapeutic option in patients with advanced pulmonary fibrosis who have a progressive course despite medical treatment, improving their survival and quality of life. It is vital that the pulmonologist knows when to refer a patient and be familiar with the requirements and contraindications. Timely referral grants
BRICEÑO V, CATALINA, SEPÚLVEDA L, CLAUDIA, MELO T, JOEL   +2 more
openaire   +2 more sources