Results 1 to 10 of about 1,840 (134)

Correction: Romero et al. Effect of Hypoxia in the Transcriptomic Profile of Lung Fibroblasts from Idiopathic Pulmonary Fibrosis. Cells 2022, 11, 3014 [PDF]

open access: yesCells
An error occurred in the original publication [...]
Yair Romero   +17 more
doaj   +2 more sources

Mitochondrial proteomics reveals reductive metabolism dependent on glutamine in fibroblasts of idiopathic pulmonary fibrosis under hypoxia [PDF]

open access: yesScientific Reports
Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), is a chronic disease characterized not only by a transcriptionally active signature associated with hypoxia but also by feedback loops that may underlie disease progression.
Yair Romero   +19 more
doaj   +2 more sources

Absence of HDAC3 by Matrix Stiffness Promotes Chromatin Remodeling and Fibroblast Activation in Idiopathic Pulmonary Fibrosis

open access: yesCells, 2023
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease characterized by progressive and irreversible lung scarring associated with persistent activation of fibroblasts.
Fernanda Toscano-Marquez   +3 more
doaj   +1 more source

Short-Term Exposure to Wood Smoke Increases the Expression of Pro-Inflammatory Cytokines, Gelatinases, and TIMPs in Guinea Pigs

open access: yesToxics, 2021
Exposure to air pollutants in wildfire smoke and indoor pollution causes lung diseases. Short-term exposure to wood smoke (WS) is partially known to alter the expression of human matrix metalloproteinases (MMPs), inflammatory cytokines, and tissue ...
Carlos Ramos   +6 more
doaj   +1 more source

Physiological and pathophysiological roles of the KCNK3 potassium channel in the pulmonary circulation and the heart

open access: yesThe Journal of Physiology, Volume 601, Issue 17, Page 3717-3737, 1 September 2023., 2023
Abstract figure legend Potassium channel subfamily K member 3 (KCNK3) is functionally expressed in pulmonary vascular and cardiac cells. KCNK3 loss of function and expression leads to pulmonary arterial hypertension (PAH) and right ventricular failure (RVF).
Anaïs Saint‐Martin Willer   +8 more
wiley   +1 more source

Síndrome combinado de fibrosis pulmonar y enfisema: albores del tratamiento antifibrótico en el Paraguay

open access: yesMemorias del Instituto de Investigaciones en Ciencias de la Salud, 2022
La concomitancia de fibrosis pulmonar en regiones inferiores del pulmón y enfisema en lóbulos superiores caracterizan a una entidad poco frecuente denominada síndrome combinado de fibrosis pulmonar y enfisema, que usualmente se asocia a alta carga de ...
Domingo Pérez-Bejarano
doaj   +1 more source

RhoA/ROCK2 signalling is enhanced by PDGF‐AA in fibro‐adipogenic progenitor cells: implications for Duchenne muscular dystrophy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 13, Issue 2, Page 1373-1384, April 2022., 2022
Abstract Background The lack of dystrophin expression in Duchenne muscular dystrophy (DMD) induces muscle fibre and replacement by fibro‐adipose tissue. Although the role of some growth factors in the process of fibrogenesis has been studied, pathways activated by PDGF‐AA have not been described so far.
Esther Fernández‐Simón   +10 more
wiley   +1 more source

FUNCIÓN PULMONAR EN FIBROSIS QUÍSTICA

open access: yesNeumología Pediátrica, 2022
La fibrosis quística (FQ) es una enfermedad hereditaria autosómica recesiva, causada por la mutación del gen que codifica la proteína CFTR (cystic fibrosis transmembrane conductance regulator), afecta varios órganos, pero la enfermedad pulmonar es la ...
Hortensia Barrientos
doaj   +1 more source

Matrix Metalloproteinases and Stress Hormones in Lung Cancer Progression

open access: yesJournal of Oncology, Volume 2022, Issue 1, 2022., 2022
Several matrix metalloproteinases (MMPs) and psychological stress are associated with poor cancer prognosis. The current work goal was to determine MMPs’ and stress hormones’ blood concentrations from lung adenocarcinoma (LAC) patients. Patients were divided into the following groups: tobacco smokers (TS), wood smoke‐exposed (W), passive smokers (PS ...
Georgina Gonzalez-Avila   +9 more
wiley   +1 more source

Pharmacokinetic evaluation of two pirfenidone formulations in patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis

open access: yesHeliyon, 2020
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease characterized by an abnormal activation of lung epithelium and fibroblasts, as well as an excessive accumulation of extracellular matrix.
Lina Marcela Barranco-Garduño   +10 more
doaj   +1 more source

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