Results 11 to 20 of about 22,028 (227)
Revista Médica Clínica Las Condes, 2015 La FPI predomina en el sexo masculino, en edades avanzadas, con tos y/o disnea progresivas. Un 5% se presenta como una forma familiar. La tomografía axial computarizada de tórax, fundamental en el diagnóstico, en al menos un 50% hace innecesaria la ...
Álvaro Undurraga P., DR.
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The Journal of Physiology, Volume 601, Issue 17, Page 3717-3737, 1 September 2023., 2023 Abstract figure legend Potassium channel subfamily K member 3 (KCNK3) is functionally expressed in pulmonary vascular and cardiac cells. KCNK3 loss of function and expression leads to pulmonary arterial hypertension (PAH) and right ventricular failure (RVF).
Anaïs Saint‐Martin Willer +8 more
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Journal of Cachexia, Sarcopenia and Muscle, Volume 13, Issue 2, Page 1373-1384, April 2022., 2022 Abstract Background The lack of dystrophin expression in Duchenne muscular dystrophy (DMD) induces muscle fibre and replacement by fibro‐adipose tissue. Although the role of some growth factors in the process of fibrogenesis has been studied, pathways activated by PDGF‐AA have not been described so far.
Esther Fernández‐Simón +10 more
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Matrix Metalloproteinases and Stress Hormones in Lung Cancer Progression
Journal of Oncology, Volume 2022, Issue 1, 2022., 2022 Several matrix metalloproteinases (MMPs) and psychological stress are associated with poor cancer prognosis. The current work goal was to determine MMPs’ and stress hormones’ blood concentrations from lung adenocarcinoma (LAC) patients. Patients were divided into the following groups: tobacco smokers (TS), wood smoke‐exposed (W), passive smokers (PS ...
Georgina Gonzalez-Avila +9 more
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Diagnóstico, 2020 Las enfermedades pulmonares intersticiales difusas (EPID) son desórdenes no neoplásicos que resultan en el daño del parénquima pulmonar con una variedad de patrones que van desde inflamación a fibrosis(1). La clasificación tradicional se enfoca primordialmente en las asociaciones conocidas subyacentes que incluyen: a) enfermedades del tejido conjuntivo
Maria Venero-Cáceres +4 more
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Oxidative Medicine and Cellular Longevity, Volume 2020, Issue 1, 2020., 2020 Introduction. Moderate aerobic exercise training accelerates the resolution of lung fibrosis in a model of bleomycin‐induced pulmonary fibrosis. However, whether it can inhibit the development of lung fibrosis is unknown. Materials and Methods. C57Bl/6 mice were distributed into four groups: Control (Co), Exercise (Exe), Bleomycin (Bleo), and Bleomycin+
Elias El-Mafarjeh +13 more
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Role of HMGB1 in Cisplatin-Persistent Lung Adenocarcinoma Cell Lines
Frontiers in Oncology, 2021 Significant advances have been made recently in the development of targeted therapy for lung adenocarcinoma. However, platinum-based chemotherapy remains as the cornerstone in the treatment of this neoplasm.
Rodolfo L. Chavez-Dominguez +11 more
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Respiratory Research, 2018 Background The main causes of COPD are tobacco smoking (COPD-TS) and biomass smoke exposure (COPD-BS). COPD-TS is known to induce changes in adipokines, incretins, and peptide hormones, frequent biomarkers of inflammation; however, it is unknown if ...
Oliver Pérez-Bautista +8 more
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Fibrosis pulmonar familiar en el síndrome de Hermansky-Pudlak
Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2022 La fibrosis pulmonar familiar en el contexto del síndrome de Hermansky-Pudlak es una entidad nosológica poco frecuente y cuyo único enfoque terapéutico definitivo es el trasplante pulmonar en los estadios avanzados.
Domingo Pérez-Bejarano
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