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Ficolin-3–mediated lectin complement pathway activation in patients with subarachnoid hemorrhage
Neurology, 2014To assess the involvement of ficolin-3, the main initiator of the lectin complement pathway (LCP), in subarachnoid hemorrhage (SAH) pathology and outcome.In this preliminary exploratory study, plasma concentration of ficolin-3 and of ficolin-3-mediated functional LCP activity was measured, along with that of other LCP initiators (mannose-binding lectin,
E. R. Zanier +10 more
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Serum Levels of Ficolin-3 (Hakata Antigen) in Patients with Systemic Lupus Erythematosus
The Journal of Rheumatology, 2009Objective.Ficolin-3 is a serum protein of putative importance in autoimmunity. Our objective was to investigate any differential expression of ficolin-3 in patients with systemic lupus erythematosus (SLE) or its clinical subsets.Methods.Serum levels of ficolin-3 (S-ficolin-3) were determined in 95 patients with SLE and 103 healthy controls using an ...
Andersen, T. +6 more
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Genetic Testing and Molecular Biomarkers, 2019
Aims: Ficolin-3 is a circulating pattern recognition molecule of the lectin pathway, which participates in the host immune responses to cancer. Our study aimed to evaluate the prognostic efficacy of ficolin-3 in patients with esophageal cancer (EC). Methods: A total of 233 patients with EC were recruited for this study during a period from March 2013 ...
Qingquan, Li, Yurong, Lin
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Aims: Ficolin-3 is a circulating pattern recognition molecule of the lectin pathway, which participates in the host immune responses to cancer. Our study aimed to evaluate the prognostic efficacy of ficolin-3 in patients with esophageal cancer (EC). Methods: A total of 233 patients with EC were recruited for this study during a period from March 2013 ...
Qingquan, Li, Yurong, Lin
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Comparative study of the human ficolins reveals unique features of Ficolin-3 (Hakata antigen)
Molecular Immunology, 2008The ficolins and mannose-binding lectin (MBL) are collagen-like defence proteins that serve as recognition molecules in lectin complement pathway. Differential features that may indicate diverse functions of these proteins are poorly understood. In this study we compared important biological features of the ficolins and MBL.
Hummelshoj, Tina +4 more
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[Proteomics study on ficolin 3 in the human plasma of type 2 diabetics].
Wei sheng yan jiu = Journal of hygiene research, 2016To explore the expression trend of ficolin 3 (FCN3) in type 2 diabetes (T2DM) plasma.Two-dimensional polyacrylamide gel electrophoresis (2DE) was used to separate the plasma proteins from T2DM patients and healthy control subjects. MALDI-TOF-TOF was used to identify the differential proteins.
Qinggang, Shang +5 more
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Fatal pneumococcus meningitis in a child with complement factor ficolin-3 deficiency
The Journal of Allergy and Clinical Immunology: In Practice, 2020Dadfar, Elham +4 more
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