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Partial Courses of Fidaxomicin Followed by Oral Vancomycin and the Effect on Recurrence of <i>Clostridioides difficile</i> Infections. [PDF]
Papamanolis IC +6 more
europepmc +1 more source
Synthesis and Biological Evaluation of Iodinated Fidaxomicin Antibiotics [PDF]
Fidaxomicin (1, tiacumicin B, lipiarmycin A3) is a marketed antibiotic that is used in the treatment of C. difficile infections. Based on the analysis of a cryo- EM structure of fidaxomicin binding to its target enzyme (RNA-polymerase), a cation-p ...
Andrea Dorst +2 more
exaly +3 more sources
Chemistry and Biology of the Clinically Used Macrolactone Antibiotic Fidaxomicin [PDF]
Fidaxomicin (1, lipiarmycin A3, clostomicin B1, tiacumicin B) constitutes a glycosylated 18-membered macrolactone and is a natural product isolated from various soil bacteria.
Andrea Dorst, Karl Gademann
exaly +2 more sources

