Results 1 to 10 of about 92,526 (264)

Evaluating the efficacy of inhaled amikacin as an adjunct to intravenous combination therapy (ceftazidime and amikacin) in pediatric cystic fibrosis pulmonary exacerbation

Frontiers in Pharmacology, 2023
Background:Pseudomonas aeruginosa is the most common microorganism found in the sputum culture of Cystic fibrosis (CF) patients causing the pulmonary destruction.
Amin Rakhshan, Nazanin Farahbakhsh, Ghamartaj Khanbabaee, Seyed Ahmad Tabatabaii, Saeed Sadr, Maryam Hassanzad, Mohammad Sistanizad, Farzaneh Dastan, Mahmoud Hajipour, Amir Reza Bahadori, Bahador Mirrahimi   +10 more
doaj   +1 more source

Acute mixed vestibulopathy. History case from the vestibulologist practice. Case report

Consilium Medicum, 2023
Patients with acute vestibulopathy are among the most uneasy (in terms of severity of symptoms) and challenging (in terms of determining the level of damage).
Sergei V. Lilenko, Dmitry S. Luppov
doaj   +1 more source

Development of a Fluorescence Polarization Assay for Multi-Determination of 10 Aminoglycosides in Pork Muscle Sample Based on Ribosomal Protein S12 and Studying Its Recognition Mechanism

Foods, 2022
The residues of aminoglycosides in foods of animal origin are a potential risk to consumers. There have been some immunoassays reported for the screening of aminoglycoside residues, but the method showing the broadest detection spectrum can only be used ...
Wanqiu Xia, Lei Zhang, Jianping Wang
doaj   +1 more source

Genomics of Aminoglycoside Resistance in Pseudomonas aeruginosa Bloodstream Infections at a United States Academic Hospital

Microbiology Spectrum, 2023
Pseudomonas aeruginosa frequently becomes resistant to aminoglycosides by the acquisition of aminoglycoside modifying enzyme (AME) genes and the occurrence of mutations in the mexZ, fusA1, parRS, and armZ genes.
Giancarlo Atassi, Rachel Medernach, Marc Scheetz, Sophia Nozick, Nathaniel J. Rhodes, Megan Murphy-Belcaster, Katherine R. Murphy, Arghavan Alisoltani, Egon A. Ozer, Alan R. Hauser   +9 more
doaj   +1 more source

Risk of Acute Kidney Injury with Amikacin versus Gentamycin both in Combination with Metronidazole for Surgical Prophylaxis [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Surgical site infection is one of the most important complication of surgery. It increases the mortality and morbidity. In order to decrease the incidence of surgical site infections perioperative antimicrobial prophylaxis has been ...
Vishal Prakash Giri, Om Prakash Giri, Subarna Bajracharya, Farhan Ahmad Khan, Shanker Prasad Sinha, Shubhra Kanodia, Chitrak Bansal   +6 more
doaj   +1 more source

Sensitization of Gram-Negative Bacteria to Aminoglycosides with 2-Aminoimidazole Adjuvants

Antibiotics, 2023
In 2019, five million deaths associated with antimicrobial resistance were reported by The Centers for Disease Control and Prevention (CDC). Acinetobacter baumannii, a Gram-negative bacterial pathogen, is among the list of urgent threats.
Ashley N. Crotteau, Veronica B. Hubble, Santiana A. Marrujo, Anne E. Mattingly, Roberta J. Melander, Christian Melander   +5 more
doaj   +1 more source

Urinary tract infection in critically ill patients with diabetes mellitus: Spectrum of uropathogens and antimicrobial susceptibility pattern

Bali Journal of Anesthesiology, 2020
Background: Urinary tract infections (UTIs) are common and more severe among patients with diabetes mellitus (DM). UTI in DM is more likely to be caused by bacteria resistant to various antimicrobials.
Nand Kishore, Sagar Modi, Sushant Khanduri, Barnali Kakati   +3 more
doaj   +1 more source

Machine Learning Establishes Single-Cell Calcium Dynamics as an Early Indicator of Antibiotic Response

Microorganisms, 2021
Changes in bacterial physiology necessarily precede cell death in response to antibiotics. Herein we investigate the early disruption of Ca2+ homeostasis as a marker for antibiotic response.
Christian T. Meyer, Megan P. Jewell, Eugene J. Miller, Joel M. Kralj   +3 more
doaj   +1 more source

Molecular mechanisms of antibiotic co-resistance among carbapenem resistant Acinetobacter baumannii

Journal of Infection in Developing Countries, 2019
Introduction: The spread of carbapenem-resistant Acinetobacter baumannii (CRAB) is difficult to control especially in the hospitals due to the successful mobilization and evolution of the genetic elements harboring the resistant determinants.
Mohsin Khurshid, Muhammad Hidayat Rasool, Muhammad Hussnain Siddique, Farrukh Azeem, Muhammad Naeem, Muhammad Sohail, Muhammad Sarfraz, Muhammad Saqalein, Zeeshan Taj, Muhammad Atif Nisar, Muhammad Usman Qamar, Asim Shahzad   +11 more
doaj   +1 more source

Aminoglycoside Antibiotics Inhibit Phage Infection by Blocking an Early Step of the Infection Cycle

mBio, 2022
In response to viral predation, bacteria have evolved a wide range of defense mechanisms, which rely mostly on proteins acting at the cellular level.
Larissa Kever, Aël Hardy, Tom Luthe, Max Hünnefeld, Cornelia Gätgens, Lars Milke, Johanna Wiechert, Johannes Wittmann, Cristina Moraru, Jan Marienhagen, Julia Frunzke   +10 more
doaj   +1 more source