Results 11 to 20 of about 69,960 (284)
, 2022 Archive of aminoglycosides containing sub-folders named after each compound and its net charge. Every compound's folder contains a total of 20 files distributed into three sub-directories reporting QM (QM/), FF (FF/), and MD (MD ...
Giuliano Malloci (2060875) +5 more
core +1 more source
Aminoglycosides : old friend... new foe? [PDF]
, 2016 Over a relatively short period, cystic fibrosis (CF) has gone from a disease of dying children to one where survival well into adulthood is expected. It was recently reported that by 2025, the adult CF population in Western Europe would increase by 75 ...
Simmonds, N.J., Thomson, A.H.
core +4 more sources
Microorganisms, 2021 Changes in bacterial physiology necessarily precede cell death in response to antibiotics. Herein we investigate the early disruption of Ca2+ homeostasis as a marker for antibiotic response.
Christian T. Meyer +3 more
doaj +1 more source
Molecular mechanisms of antibiotic co-resistance among carbapenem resistant Acinetobacter baumannii
Journal of Infection in Developing Countries, 2019 Introduction: The spread of carbapenem-resistant Acinetobacter baumannii (CRAB) is difficult to control especially in the hospitals due to the successful mobilization and evolution of the genetic elements harboring the resistant determinants.
Mohsin Khurshid +11 more
doaj +1 more source
Aminoglycoside Antibiotics Inhibit Phage Infection by Blocking an Early Step of the Infection Cycle
mBio, 2022 In response to viral predation, bacteria have evolved a wide range of defense mechanisms, which rely mostly on proteins acting at the cellular level.
Larissa Kever +10 more
doaj +1 more source
Antibiotics, 2021 Aminoglycoside or colistin therapy may alter the renal tubular function without decreasing the glomerular filtration rate. This association has never been extensively investigated.
Martin Scoglio +10 more
doaj +1 more source
Unwarranted use of intravenous aminoglycosides at UK paediatric cystic fibrosis centres [PDF]
, 2019 Highlights IV aminoglycosides are frequently used to treat infective exacerbations in CF due to efficacy against PA.The side effects of aminoglycosides include nephrotoxicity, ototoxicity and vestibulotoxicity.More than one third of UK CF centres use ...
Carroll, W.D. +2 more
core +1 more source
Designer aminoglycosides prevent cochlear hair cell loss and hearing loss. [PDF]
, 2015 Bacterial infections represent a rapidly growing challenge to human health. Aminoglycosides are widely used broad-spectrum antibiotics, but they inflict permanent hearing loss in up to ~50% of patients by causing selective sensory hair cell loss.
Alan G. Cheng +21 more
core +2 more sources
The Pharmacodynamics of Aminoglycosides [PDF]
Clinical Infectious Diseases, 1998 Recently, a more complete understanding of the pharmacodynamics of aminoglycosides has been recognized, indicating that this class of antibiotics exhibits both concentration-dependent bactericidal activity and a postantibiotic effect. This pharmacodynamic information, along with better knowledge of the mechanisms responsible for aminoglycoside toxicity,
M K, Lacy +3 more
openaire +2 more sources