Results 21 to 30 of about 69,960 (284)

Sustained Neuromuscular Blockade after Vecuronium Use in a Premature Infant

American Journal of Perinatology Reports, 2015
Background Prolonged use of neuromuscular blocking agents (NMBAs) is very common in critically ill children both in pediatric and neonatal intensive care units. There are no guidelines available for use of NMBAs in children or neonates in the US, and the
Mitali Sahni, C. Joan Richardson, Sunil K. Jain   +2 more
doaj   +1 more source

Pre-habilitation Before Vestibular Schwannoma Surgery—Impact of Intratympanal Gentamicin Application on the Vestibulo-Ocular Reflex

Frontiers in Neurology, 2021
Background: Patients with vestibular schwannoma that show residual peripheral-vestibular function before surgery may experience sudden and substantial vestibular loss of function after surgical resection.
Alexander A. Tarnutzer, Alexander A. Tarnutzer, Alexander A. Tarnutzer, Alexander A. Tarnutzer, Christopher J. Bockisch, Christopher J. Bockisch, Christopher J. Bockisch, Christopher J. Bockisch, Elena Buffone, Alexander M. Huber, Vincent G. Wettstein, Vincent G. Wettstein, Konrad P. Weber, Konrad P. Weber, Konrad P. Weber, Konrad P. Weber   +15 more
doaj   +1 more source

RmtC and RmtF 16S rRNA Methyltransferase in NDM-1–Producing Pseudomonas aeruginosa

Emerging Infectious Diseases, 2015
We investigated 16S rRNA methyltransferases in 38 blaNDM-1–positive Pseudomonas aeruginosa isolates and found RmtC in 3 isolates, 1 of which also harbored RmtF.
Mohibur Rahman, Kashi Nath Prasad, Ashutosh Pathak, Binod Kumar Pati, Avinash Singh, Cristina M. Ovejero, Saheem Ahmad, Bruno Gonzalez-Zorn   +7 more
doaj   +1 more source

Integrated Microfluidic Devices Fabricated in Poly (Methyl Methacrylate) (PMMA) for On-site Therapeutic Drug Monitoring of Aminoglycosides in Whole Blood

Biosensors, 2019
On-site therapeutic drug monitoring (TDM) is important for providing a quick and accurate dosing to patients in order to improve efficacy and minimize toxicity.
Zaidon T. Al-aqbi, Yiing C. Yap, Feng Li, Michael C. Breadmore   +3 more
doaj   +1 more source

Antimicrobial Synergy between Aminoglycosides and Licorice Extract in Listeria monocytogenes

Pathogens, 2022
Listeria monocytogenes is a foodborne pathogen that can develop serious invasive infections. Among foodborne pathogens, L. monocytogenes exhibits the highest case fatality despite antibiotic treatment, suggesting the current therapy should be improved ...
Myungseo Park, Liz Horn, Victoria Lappi, Dave Boxrud, Craig Hedberg, Byeonghwa Jeon   +5 more
doaj   +1 more source

Bioenergetic State of Escherichia coli Controls Aminoglycoside Susceptibility

mBio, 2023
Aminoglycosides (AG) have been used against Gram-negative bacteria for decades. Yet, how bacterial metabolism and environmental conditions modify AG toxicity is poorly understood.
Jessica Y. El Khoury, Jordi Zamarreño Beas, Allison Huguenot, Béatrice Py, Frédéric Barras   +4 more
doaj   +1 more source

Aminoglycoside and Nephrotoxicity

Kidney and Blood Pressure Research, 1987
The effect of three aminoglycosides – gentamicin, netilmicin and amikacin – on renal acid excretion was studied in male rats treated with doses equivalent to those clinically used. The amikacin and netilmicin groups showed no important changes in the values of glomerular filtration rate (GFR), effective renal plasma flow (ERPF) and U/P inulin ratio ...
V L, Silva, F Z, Gil, G, Nascimento, M F, Cavanal   +3 more
openaire   +2 more sources

Antibacterial Efficacies of Nanostructured Aminoglycosides

, 2022
The widespread use of broad-spectrum aminoglycoside antibiotics is restricted from various clinical applications due to the emergence of bacterial resistance and the adverse effects such as ototoxicity and nephrotoxicity.
Dhananjoy Mondal, Smritilekha Bera, Dhananjoy Mondal (2224102), Smritilekha Bera (2117740)   +3 more
core   +1 more source

Hearing in 44-45 year olds with m.1555A > G, a genetic mutation predisposing to aminoglycoside-induced deafness: a population based cohort study. [PDF]

, 2012
Background The mitochondrial DNA mutation m.1555A>G predisposes to permanent idiosyncratic aminoglycoside-induced deafness that is independent of dose.
Pearce, K, Rahman, S, Costello, H, Sweeney, MG, Ecob, R, Bitner-Glindzicz, M, Duncan, AJ, Strachan, D, Forge, A, Davis, A   +9 more
core   +1 more source

KI04 an Aminoglycosides-Derived Molecule Acts as an Inhibitor of Human Connexin46 Hemichannels Expressed in HeLa Cells

Biomolecules, 2023
Background: Connexins (Cxs) are proteins that help cells to communicate with the extracellular media and with the cytoplasm of neighboring cells. Despite their importance in several human physiological and pathological conditions, their pharmacology is ...
Cheng-Wei T. Chang, Naveena Poudyal, Daniel A. Verdugo, Francisca Peña, Jimmy Stehberg, Mauricio A. Retamal   +5 more
doaj   +1 more source