Results 31 to 40 of about 92,526 (264)

Influência dos polimorfismos da glutationa s-transferase na ototoxicidade dos aminoglicosídeos Influence of glutathione s-transferase on the ototoxicity caused by aminoglycosides

open access: yesBrazilian Journal of Otorhinolaryngology, 2010
O processo de morte e danos em células ciliadas devido à exposição ao ruído e ototoxinas parece ser mediado por espécies reativas de oxigênio. OBJETIVO: Investigar a relação entre polimorfismos gênicos na Glutationa S-transferase e a susceptibilidade à ...
Bruna Palodetto   +4 more
doaj   +1 more source

Transcriptome profiling in response to Kanamycin B reveals its wider non-antibiotic cellular function in Escherichia coli

open access: yesFrontiers in Microbiology, 2022
Aminoglycosides are not only antibiotics but also have wider and diverse non-antibiotic cellular functions. To elucidate the understanding of non-antibiotic cellular functions, here we report transcriptome-profiling analysis of Escherichia coli in the ...
Yaowen Chang   +3 more
doaj   +1 more source

The Impact of an Efflux Pump Inhibitor on the Activity of Free and Liposomal Antibiotics against Pseudomonas aeruginosa

open access: yesPharmaceutics, 2021
The eradication of Pseudomonas aeruginosa in cystic fibrosis patients has become continuously difficult due to its increased resistance to treatments.
Douweh Leyla Gbian, Abdelwahab Omri
doaj   +1 more source

Synergistic Activity of Fosfomycin, Ciprofloxacin, and Gentamicin Against Escherichia coli and Pseudomonas aeruginosa Biofilms [PDF]

open access: yes, 2019
Gram-negative (GN) rods cause about 10% periprosthetic joint infection (PJI) and represent an increasing challenge due to emergence of antimicrobial resistance.
Di Luca, Mariagrazia   +4 more
core   +1 more source

Cellular glutathione content in the organ of Corti and its role during ototoxicity. [PDF]

open access: yes, 2015
Glutathione (GSH) is the major scavenger of reactive oxygen species (ROS) inside cells. We used live confocal imaging in order to clarify the role of GSH in the biology of the organ of Corti, the sensory epithelium of the cochlea, before, during and ...
Duchen, MR, Gale, JE, Majumder, P
core   +1 more source

Positive Bacterial Culture among Adults with Suspected Urinary Tract Infections Presenting to the Department of Medicine of a Tertiary Care Centre

open access: yesJournal of Nepal Medical Association
Introduction: Urinary tract infections are the most common infections encountered in clinical practice. Treatment needs to take into account the likely organism, comorbidities and local antibiotic sensitivity pattern.
Bishnu Jwarchan   +3 more
doaj   +1 more source

Synthesis of 6″-Modified Kanamycin A Derivatives and Evaluation of Their Antibacterial Properties

open access: yesPharmaceutics, 2023
Aminoglycosides are one of the first classes of antibiotics to have been used clinically, and they are still being used today. They have a broad spectrum of antimicrobial activity, making them effective against many different types of bacteria.
Kseniya Shapovalova   +6 more
doaj   +1 more source

Transfer of antibiotic resistance in Staphylococcus aureus [PDF]

open access: yes, 2017
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob   +2 more
core   +1 more source

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

open access: yes, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania   +19 more
core   +1 more source

Phytochemical analysis and modulation in aminoglycosides antibiotics activity by Lantana camara L.

open access: yesActa Scientiarum: Biological Sciences, 2015
Several plants have been evaluated not only for alone antimicrobial activity, but as resistance-modifying agent. This work is the first on the modulation of antibiotic activity by Lantana camara L.
Erlânio Oliveira de Sousa   +3 more
doaj   +1 more source

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