Results 41 to 50 of about 4,025 (198)

Fidaxomicin Use in the Pediatric Population with Clostridioides difficile

open access: yesClinical Pharmacology: Advances and Applications, 2022
Meredith B Oliver,1 Byron P Vaughn2 1M Health Fairview, Masonic Children’s Hospital, Minneapolis, MN, USA; 2Division of Gastroenterology, Hepatology, and Nutrition, University of Minnesota, Minneapolis, MN, USACorrespondence: Byron P Vaughn, Department ...
Oliver MB, Vaughn BP
doaj  

Is Three Company or a Crowd? Comparing and Contrasting U.S. and European Clostridioidesdifficile Clinical Practice Guidelines

open access: yesAntibiotics, 2022
In 2021, the American College of Gastroenterology (ACG), the Infectious Diseases Society of America in conjunction with the Society for Healthcare Epidemiology of America (IDSA/SHEA), and the European Society of Clinical Microbiology and Infectious ...
Jordan Jones   +4 more
doaj   +1 more source

High in vitro activity of fidaxomicin against Clostridium difficile isolates from a university teaching hospital in China

open access: yesJournal of Microbiology, Immunology and Infection, 2018
Background: Clostridium difficile infection (CDI) is a significant cause of morbidity and mortality in both the acute care setting and the wider healthcare system.
Jing-Wei Cheng   +8 more
doaj   +1 more source

Tigecycline combination therapy for fulminant Clostridioides difficile infection: an Australian experience

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop   +5 more
wiley   +1 more source

Impact of the use of local fidaxomicin treatment algorithms for managing Clostridium difficile infection in hospitalized patients in southeastern United States

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2018
Background Clostridium difficile-associated diarrhea (CDAD) is a major public health threat that results in increased length of stay, hospital readmissions, deaths, and economic burden. CDAD treatment is often guided by severity of disease.
Jonathan C. Cho   +4 more
doaj   +1 more source

Laboratory‐Detected Clostridioides difficile Stool‐Test Positivity and Mortality in Sepsis: A Retrospective Cohort Study

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Sepsis disrupts intestinal microbiota, and broad‐spectrum antibiotics may worsen dysbiosis. Clostridioides difficile (C. difficile) infection (CDI) is a prevalent nosocomial enteric pathogen among critically ill patients, yet its prognostic implications in sepsis remain inadequately studied.
Jiyun Hu   +6 more
wiley   +1 more source

Clostridioides difficile as a Zoonotic and Foodborne Pathogen: Reviewing the Global Evidence and South African Data

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Clostridioides difficile infections are increasingly problematic in areas with already burdened healthcare systems. From a One‐Health perspective, a lack of surveillance in developing countries greatly contributes to the limited information available on the zoonotic and foodborne potential of C. difficile.
M. Gouws, P. E. Strydom, D. Rip
wiley   +1 more source

Nanjing Consensus II on Washed Microbiota Transplantation: Statements From the CHINAGUT Conference

open access: yesMicrobiota Medicine Research, Volume 1, Issue 2, Page 45-62, June 2026.
ABSTRACT The new method of fecal microbiota transplantation, based on automatic facilities and washing processes, was coined as washed microbiota transplantation (WMT). The first recommendations on WMT were released as Nanjing Consensus report by the fecal microbiota transplantation (FMT)‐standardization Study Group in 2019.
Faming Zhang   +53 more
wiley   +1 more source

Reduction in Clostridium difficile environmental contamination by hospitalized patients treated with fidaxomicin. [PDF]

open access: yes, 2015
Fidaxomicin is sporicidal and may be associated with a reduced time to resolution of diarrhoea when used to treat patients with Clostridium difficile infection (CDI).
Wade, P   +13 more
core   +1 more source

A roadmap for designing narrow-spectrum antibiotics targeting bacterial pathogens

open access: yesMicrobial Cell, 2022
Clostridioides difficile (Cdiff) infection (CDI) continues to be the leading threat of nosocomial deaths worldwide and a major burden on health-care systems.
Xinyun Cao   +2 more
doaj   +1 more source

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