Results 41 to 50 of about 7,649,591 (233)

Estimates of the field-aligned current density in current-carrying filaments using auroral zone ground-based observations [PDF]

, 2001
International audienceWe described the ground signatures of dynamic substorm features as observed by the imaging riometer, magnetometers and all-sky camera (ASC) at Kilpisjärvi, Finland on 5 and 25 October 1999 during the late evening hours.
Danielides, M.A., M. A. Danielides, J. Kangas, Shalimov, S., S. Shalimov, Danielides, M. A., Kangas, J.   +6 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Statistical average estimates of high latitude field-aligned currents from the STARE and SABRE coherent VHF radar systems [PDF]

, 2001
Nielsen, E., Kosch, M. J.
core   +5 more sources

Field‐Aligned Currents Induced by Magnetopause Motions Under Pressure Perturbations

Geophysical Research Letters
In this work, we identified 65 auroral arcs that stretched out from the equatorward boundary of auroral oval with azimuthal extensions, and investigated their upstream triggering, by utilizing conjunctions between the THEMIS probes and the all‐sky ...
Boyi Wang, Xinyu Xu, Yukitoshi Nishimura, Yen‐Jung Wu, Zhonghua Xu, Primož Kajdic, De‐Sheng Han, Yi Wang, Xueshang Feng   +8 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

On the structure of field-aligned currents in the mid-altitude cusp [PDF]

Annales Geophysicae, 2006
We analyse two crossings of the polar cusp at mid-altitudes (≈4 RE) by Cluster in order to study the structure of field-aligned currents associated with the injection of magnetosheath plasma.
A. Marchaudon, A. Marchaudon, J.-C. Cerisier, J.-M. Bosqued, C. J. Owen, A. N. Fazakerley, A. D. Lahiff   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source