Results 71 to 80 of about 7,649,591 (233)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Auroral Energy Flux and Joule Heating Derived From Global Maps of Field-Aligned Currents. [PDF]

Geophys Res Lett, 2021
Robinson RM, Zanetti LJ.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Spatial and Temporal Evolution of Different‐Scale Ionospheric Irregularities in Central and East Siberia During the 27–28 May 2017 Geomagnetic Storm

Space Weather, 2020
We present a multi‐instrumental study of ionospheric irregularities of different scales (from tens of centimeters to few kilometers) observed over the Central and East Siberia, Russia, during a moderate‐to‐strong geomagnetic storm on 27–28 May 2017. From
V. B. Ovodenko, M. V. Klimenko, I. E. Zakharenkova, A. V. Oinats, D. S. Kotova, A. V. Nikolaev, I. V. Tyutin, D. D. Rogov, K. G. Ratovsky, D. V. Chugunin, P. A. Budnikov, J. C. Coxon, B. J. Anderson, A. A. Chernyshov   +13 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

First E region observations of mesoscale neutral wind interaction with auroral arcs [PDF]

, 2010
We report the first observations of E region neutral wind fields and their interaction with auroral arcs at mesoscale spatial resolution during geomagnetically quiet conditions at Mawson, Antarctica.
Fiori, R. A. D., Kosch, Mike J., Anderson, C., Makarevich, R. A., Carter, B. A., Davies, T., Conde, M., Dyson, P. L.   +7 more
core   +3 more sources

First Detection of Field‐Aligned Currents Using Engineering Magnetometers From the OneWeb Mega‐Constellation

Space Weather
Field‐aligned currents (FACs) are the main physical mechanism behind magnetosphere–ionosphere coupling, with these currents communicating environmental changes between the two regions of geospace.
Martin O. Archer, Vincent Evans, Jonathan P. Eastwood, Louis‐Ashley Camus, Cara L. Waters, Patrick Brown, Fabien Armogathe   +6 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Ionospheric F-region currents estimated from Macau Science Satellite-1 and Swarm satellite magnetic data

Earth and Planetary Physics
Accurate modeling of Earth’s ionospheric F-region currents is essential for refining geomagnetic field models and understanding magnetosphere-ionosphere coupling.
JuYuan Xu, HongBo Yao, Keke Zhang
doaj   +1 more source