Results 71 to 80 of about 123,835 (272)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Iron biogeochemistry across marine systems progress from the past decade [PDF]

, 2010
Based on an international workshop (Gothenburg, 14–16 May 2008), this review article aims to combine interdisciplinary knowledge from coastal and open ocean research on iron biogeochemistry. The major scientific findings of the past decade are structured
Achterberg, E. P., Ardelan, M. V., Baker, A. R., Breitbarth, E., Bucciarelli, E., Chever, F., Croot, P. L., Duggen, S., Gledhill, M., Hassellöv, M., Hassler, C., Hoffmann, L. J., Hunter, K. A., Hutchins, D. A., Ingri, J., Jickells, T., Lohan, M. C., Nielsdό, Sarthou, G., Schoemann, V., Trapp, J. M., Turner, D. R., Ye, Ying   +22 more
core   +5 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Gel filtration chromatography [PDF]

, 2011
Gel-filtration chromatography is a popular and versatile technique that permits the effective separation of proteins and other biological molecules in high yield. Here, the basis of the method is described and typical matrix types are contrasted.
Cummins, Phil, O'Connor, Brendan, Ó Fágáin, Ciarán   +2 more
core  

Efficiency of size-dependent particle separation by pinched flow fractionation

, 2012
Pinched flow fractionation is shown to be an efficient and selective way to quickly separate particles by size in a very polydisperse semi-concentrated suspension. In an effort to optimize the method, we discuss the quantitative influence of the pinching
Coupier, Gwennou, Podgorski, Thomas, Srivastav, Aparna   +2 more
core   +4 more sources

Soil methane sink capacity response to a long-term wildfire chronosequence in Northern Sweden [PDF]

, 2015
Boreal forests occupy nearly one fifth of the terrestrial land surface and are recognised as globally important regulators of carbon (C) cycling and greenhouse gas emissions.
A Liptay, A Priemé, AJ Soja, Andy Stott, APS Adamsen, ASK Chan, C Knief, CJA Bradshaw, DA Wardle, DA Wardle, DA Wardle, DA Wardle, David A. Wardle, DS Reay, E Chuvieco, EA Holland, ES Kasischke, ES Kasischke, G Girardin, J. Colin Murrell, K Jaatinen, KA Smith, M Ohlson, MA Gathany, Md. Tanvir Rahman, N Pluchon, Niall P. McNamara, Nick J. Ostle, NP McNamara, PJ Maxfield, PSA Beck, R. Michael Lehman, RA Burke, Richard D. Bardgett, Ruth Gregg, S Sjögersten, SC Tyler, Simon Oakley, T Nakano, WS Reeburgh, Y-H Zhang, YA Teh, YA Trotsenko   +42 more
core   +3 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Effects of Angular Dependency of Particulate Light Scattering Intensity on Determination of Samples with Bimodal Size Distributions Using Dynamic Light Scattering Methods

Nanomaterials, 2018
The angular dependency of light scattering intensity from differently sized particles strongly influences the apparent particle size distribution, as determined by dynamic light scattering (DLS) methods. Manufactured nanomaterials have size distributions
Haruhisa Kato, Ayako Nakamura, Shinichi Kinugasa   +2 more
doaj   +1 more source

Intercomparison of soil pore water extraction methods for stable isotope analysis [PDF]

, 2016
Funded by NSERC Discovery Grant U.S. Forest Service U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy, Bioenergy Technologies OfficePeer ...
McDonnell, Jeffery J., Orlowski, Natalie, Pratt, Dylan L.   +2 more
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source