Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Anti-Corruption Science Mapping Based on ISI Sciences Citation Database Articles [PDF]
مطالعات مدیریت بهبود و تحولThe purpose of this study is to draw a map of anti-corruption science. For this purpose, in the first step, the glossary of anti- corruption was determined to better understand this category .Then the ISI database and related sites were selected as the ...
saeed zarandi, ahmad sedaqatpisheh
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
B1 field map synthesis with generative deep learning used in the design of parallel-transmit RF pulses for ultra-high field MRI. [PDF]
Z Med Phys, 2022 Eberhardt B +3 more
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Co-Concept Analysis in Bioinformatics Field by Yewno Based on Experts’ Viewpoints
International Journal of Information Science and Management, 2020 In this paper, the opinions of bioinformatics experts were sought to examine the knowledge semantic maps. The research question was whether the mapping of bioinformatics field articles could contribute to the reflection of knowledge map in this field ...
Masoume Kiani +3 more
doaj
Gray Images of Constacyclic Codes Over Some Polynomial Residue Rings
پژوهشهای ریاضی, 2021 Let be the quotient ring where is the finite field of size and is a positive integer. A Gray map of length over is a special map from to ( .
Reza Sobhani
doaj
Simultaneous changes in visual acuity, cortical population receptive field size, visual field map size, and retinal thickness in healthy human aging. [PDF]
Brain Struct Funct, 2021 Silva MF +7 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source