Results 41 to 50 of about 16,843,566 (279)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

AI-BASED FIELD-ORIENTED CONTROL FOR INDUCTION MOTORS

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
The current article deals with the implementation of Reinforcement Learning based Field Oriented Control (FOC) for the induction motors (IM). It is pertinent to mention that although conventional controllers like PID are widely used in FOC induction ...
Elmehdi Benmalek, Marouane Rayyam, Ayoub Gege, Omar Ennasiri, Adil Ezzaidi   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Simulation of Field Oriented Control in Induction Motor Drive System [PDF]

, 2013
In this paper, a 3-phase induction motor model for simulation the field oriented control (FOC) system based on space vector pulse width modulation (SVPWM) is established in Ansoft/Simplorer software.
Zhang, Haijiao, Zhang, Jingxiong, Zhao, Xiang, Liu, Huijuan   +3 more
core   +2 more sources

Model-Based Predictive Rotor Field-Oriented Angle Compensation for Induction Machine Drives

Energies, 2021
In this paper, a model-based predictive rotor field-oriented angle compensation approach is proposed for induction machine drives. Indirect rotor field-oriented control is widely used in induction machine drives for its simple implementation and low cost.
Yang Liu, Jin Zhao, Quan Yin
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

A sensor fault-tolerant control solution based on current observers applied to three phase induction motor drive

Journal of Advanced Engineering and Computation, 2023
This paper presents a fault-tolerant control (FTC) solution to enhance the reliability and sustainability of a three-phase induction motor drive (IMD) against open circuit sensor failures (or total sensor faults).
Cuong Dinh Tran, Giang Thi Tuyet Lai, Thao Minh Ca, Thong Tien Nguyen, Phuong Duy Nguyen   +4 more
doaj   +1 more source