Results 41 to 50 of about 144,020 (259)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Wheat cultivars grain yield and quality traits variability under conditions of southern Pannonian plain [PDF]

open access: yesRatarstvo i Povrtarstvo
In order to meet milling industry and grain producers' requirements, wheat grain needs to possess good technological quality, and high and stable grain production.
Timić Jovana   +6 more
doaj   +1 more source

Seed vitality of sunflower inbred lines influenced by meteorological factors and seed size [PDF]

open access: yesJournal on Processing and Energy in Agriculture, 2022
Climate changes inevitably affect plant production, but it is difficult to predict their direct impact on a vitality (germination) of a produced seed.
Krstić Miloš   +6 more
doaj  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Morphological and molecular identification of Fusarium tricinctum and Fusarium acuminatum as causal agents of garlic bulbs rot in Serbia [PDF]

open access: yesZbornik Matice Srpske za Prirodne Nauke, 2017
Garlic (Allium sativum L.) is considered to be one of the oldest crops in the world. During 2016, infected garlic bulbs occurred in storages on several localities of the Province of Vojvodina.
Ignjatov Maja V.   +6 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

GGE biplot analysis of sugar beet multi-environment trials [PDF]

open access: yesRatarstvo i Povrtarstvo, 2017
Multi-environment trials are performed every year with the aim of evaluating sugar beet varieties in different environmental conditions of Serbia.
Ćurčić Živko   +5 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Drought effect on maize seedling development [PDF]

open access: yesRatarstvo i Povrtarstvo, 2018
Drought stress is one of the most important abiotic stresses influencing performance of crops. Certain stress-related conditions can appear and slow down germination, seedling development and in some cases cause loss of life durability of seed.
Radić Velimir   +5 more
doaj  

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