Results 51 to 60 of about 160,658 (219)

Determination of the optimal doses of gamma irradiation for induced mutation in wheat and barley [PDF]

Ratarstvo i Povrtarstvo
One of the major challenges that plant breeders face in the 21st century is food safety for growing human population coupled with extreme climate changes.
Glogovac Svetlana, Trkulja Dragana, Kondić-Špika Ankica, Mirosavljević Milan, Jocković Bojan, Brbaklić Ljiljana, Miladinović Dragana   +6 more
doaj   +1 more source

SIMULTANEOUS SELECTION FOR HIGH YIELDING AND STABILITY OF SOME ECONOMIC KENAF CHARACTERS [PDF]

Journal of Plant Production, 2012
           The materials used for the present study consisted of fourteen kenaf genotypes (G) which were evaluated over six environments (three at Ismailia Governorate, two at Giza Governorate and one at El-Beheira Governorate) through three successive ...
T. Omar, Amany El-Refaie, H. Abo- Kaied
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

GEMMEIZA 11 – A NEW EGYPTIAN HIGH YIELDING BREAD WHEAT (Triticum aestivum L.) CULTIVAR [PDF]

Journal of Plant Production, 2013
The newly bread wheat cultivar Gemmeiza 11 has been selected from a local cross made at Gemmeiza Agricultural Research Station, Wheat Research Dept. FCRI, ARC. Egypt, using the pedigree method. Yield evaluation was performed through 10 preliminary yield
S. Abdel- Dayem, Nadia Abd El-Nour, Wafaa El- Awady, M. El- Shamy, I. Imbaby, F. Hefnawy, Najwa Abdel- Fattah, A. El-Hag, A. Abdel-Latif, A. Khattab, M. Salem, S. Sabry, M. Abde-Aleem, T. Shehab El Din, M. Sharshar, M. Mostafa, M. Gouda, M. Moussa, N. Hanna, M. Mosaad, S. Mahmoud, Enayat Ghanem, A. Gomaa, M. Abdel Kader, Shereen Nathan, I. Abdel- Latif, Ragab Gad, E. Abd El-Hamid, W. Farahat, M. Aglan, Hoda El-Gharabawy, A. Morsy, Thanaa Abd-El-Kreem, M. Moubark, M. Mahmoud, A. Hagras, Aza Abdel–Al, M. El-Maghraby, A. Gad-Allah, Manal Hassan, M. Zakaria, I. Amin, R. Ramadan, M. Khaled, Sabah Abo El-Ela, Magda Abdel – Rahman, S. Hamad, S. El- Sawy, A. Swelam, Sohair Hassan, A. Menshawy, H. El-Borhamy, A. Mostafa, Hayam Mahgoub, H. Hendawy, M. Toweefles, H. Ashoush, E. El-Sayed, M. Mesherf, A. Tammam, A. Abo- Warda, S. Abdel- Majeed, A. morad, G. El- Shaarawy, S. Sleem, R. Kumber, A. Moussa, A. Hamada, M. Abo Shereef, M. El-Menofy, A. Ageez, Eman Sadek   +71 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Wheat cultivars grain yield and quality traits variability under conditions of southern Pannonian plain [PDF]

Ratarstvo i Povrtarstvo
In order to meet milling industry and grain producers' requirements, wheat grain needs to possess good technological quality, and high and stable grain production.
Timić Jovana, Dražić Tanja, Mirosavljević Milan, Jocković Bojan, Aćin Vladimir, Mikić Sanja, Brbaklić Ljiljana   +6 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source