Results 41 to 50 of about 1,198,046 (263)

Metabolic stress in space: ROS-induced mutations in mice hint at a new path to cancer

open access: yesRedox Biology
Long-duration spaceflight beyond Earth's magnetosphere poses serious health risks, including muscle atrophy, bone loss, liver and kidney damage, and the Spaceflight-Associated Neuro-ocular Syndrome (SANS).
Viktor Stolc   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Multiple airy beams light-sheet fluorescence microscopy

open access: yesFrontiers in Physics, 2022
Light-sheet fluorescence microscopy (LSFM) is a kind of volumetric imaging methodology suited for long term living specimens at high temporal-spatial resolution.
Shuangyu Gu   +9 more
doaj   +1 more source

A Sustainable Scheme for Minimizing Energy in Visual Sensor Network using Disjoint Set Cover Approach [PDF]

open access: yesEngineering and Technology Journal, 2020
Directional sensors in wireless visual sensor networks attract growing attention as a promising tool for monitoring the real world; directional sensors consume energy for two main tasks: sensing and communication.
Shuruq Hashim, Muna Jawad, Bassam Wheedd
doaj   +1 more source

Field-of-view extension for VR viewers [PDF]

open access: yesProceedings of the 21st International Academic Mindtrek Conference, 2017
We present a prototype of a smartphone-based virtual reality (VR) viewer, which can cover nearly the full human field-of-view (FOV). The prototype suggests that such extensions are feasible ways to significantly expand the FOV of standard VR viewers. The concept can be employed for future VR viewers or it can even be retrofitted to some existing ones.
Ismo Rakkolainen   +3 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Role of Polycyclic Aromatic Hydrocarbons with Edge Defects in Explaining Astronomical Infrared Emission Observations

open access: yesThe Astrophysical Journal
A systematic study was performed on the spectral properties of polycyclic aromatic hydrocarbons (PAHs) with edge defects using harmonic density functional theory calculations.
A. Ricca   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Toward Inferring the Surface Fluxes of Biosignature Gases on Rocky Exoplanets from Telescope Spectra

open access: yesThe Astrophysical Journal
The James Webb Space Telescope and the future Habitable Worlds Observatory aim to discover exoplanet atmospheric spectra that detect life. Currently, most existing spectral “retrieval” algorithms focus on inferring the abundances of biogenic gases from ...
Nicholas F. Wogan   +7 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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