Results 71 to 80 of about 1,198,046 (263)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

High-resolution multi-modal imaging of sub-cellular structures with low numerical aperture objective

open access: yesJPhys Photonics
Imaging of subcellular structures, which underpins many of the advances in biological and medical sciences, requires microscopes with high numerical aperture (N.A.) objectives which are costly, complex, requires oil immersion and have very limited field ...
Somaiyeh Khoubafarin   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Toroidal Magnetic Flux Budget in Mean-field Dynamo Model of Solar Cycles 23 and 24

open access: yesThe Astrophysical Journal
We study the toroidal magnetic flux budget of the axisymmetric part of a data-driven 3D mean-field dynamo model of Solar Cycles 23 and 24. The model simulates the global solar dynamo that includes the effects of the formation and evolution of bipolar ...
Valery V. Pipin, Alexander G. Kosovichev
doaj   +1 more source

Optimized Multiple Unmanned Surface Vehicle Strategies for Target Tracking with Field of View Constraints

open access: yesJournal of Marine Science and Engineering
Unmanned surface vehicles (USVs) have garnered significant interest due to their potential in various maritime applications, particularly target tracking.
Kai Xue   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Kiladze Caldera: A Possible Cryovolcano on Pluto

open access: yesThe Planetary Science Journal
In contrast with regional primarily methane composition, Kiladze and its surroundings exhibit a water-ice spectral signature that carries an ammoniated compound, similar to two other cryovolcanic sites on Pluto.
A. Emran   +4 more
doaj   +1 more source

Influence of Field of View and Bowtie Filtration on Cone Beam Computed Tomography Image Quality and Scatter-to-Primary Ratio

open access: yesJournal of Medical Physics
Purpose/Aim: The image quality (IQ) of cone-beam computed tomography (CBCT) is often reduced due to X-ray scatter, causing issues such as shading, skin-line artifacts, decreased contrast-to-noise ratio, and inaccurate computed tomography (CT) numbers ...
Noor Mail   +2 more
doaj   +1 more source

A Parametric Method for Remapping and Calibrating Fisheye Images for Glare Analysis

open access: yesBuildings, 2019
High Dynamic Range (HDR) imaging using a fisheye lens has provided new opportunities to evaluate the luminous environment in visual comfort research.
Ayman Wagdy   +3 more
doaj   +1 more source

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