Results 81 to 90 of about 572,960 (261)

Identification and provenance analysis of sediments’ end-members in the typical black soil area of northeast China

Frontiers in Earth Science
IntroductionThe Songnen Plain is a significant black soil region in China, where the sedimentary processes and provenance of sediments are crucial for reconstructing the regional environmental evolution.MethodsIn this study, end-member modeling analysis ...
Peng Chen, Peng Chen, Peng Chen, Jiahao Qi, Jiahao Qi, Junchi Ma, Junchi Ma, Yuan Jing, Yuan Jing, Hao Sun, Hao Sun, Chunpeng Wang, Chunpeng Wang, Jiangyin Huang, Jiangyin Huang   +14 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Effect of Land Cover Type on 3D Deformation Recovery From Synthetically Deformed High Resolution Satellite Optical Imagery

Earth and Space Science
The limits of detection for earthquake surface deformation in the spatial domain have improved with advances in remote sensing imagery data availability, resolution, and analysis.
C. Hanagan, S. B. DeLong, N. G. Reitman
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Seismotectonics of the Philippine and Taiwan Subduction Systems and Implications for Seismic Hazards

Geochemistry, Geophysics, Geosystems
The seismicity of the Philippines and Taiwan provides insight into the tectonics and seismic hazards of a region characterized by subduction and collision.
Sean J. Hutchings, Walter D. Mooney
doaj   +1 more source

Field survey data on the effectiveness of agrometeorological services for smallholder farmers in Niger. [PDF]

Data Brief, 2023
Bacci M, Zini C, Idrissa OA, Burrone S, Tsayabou A, Maïga SS, Sitta AA, Tarchiani V.   +7 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Conducting Ethical Field Research on Rape in West African Settings: Case Study of 2018 Liberian Field Survey. [PDF]

Healthcare (Basel), 2023
Hanson-DeFusco J, Smith EG, Ngafuan RF, Dunn WN.   +3 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Field survey of Cassidinae beetles (Coleoptera, Chrysomelidae) and their host plants in southern Guangxi, China. [PDF]

Biodivers Data J, 2023
Yang C, Liao C, Xu J, Liu P, Staines CL, Dai X.   +5 more
europepmc   +1 more source