Results 81 to 90 of about 2,133,710 (299)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Kink scattering in the presence of geometric constrictions
Journal of High Energy Physics, 2023 We investigate kink-antikink collisions in a model characterized by two scalar fields in the presence of geometric constrictions. The model includes an auxiliary function that modifies the kinematics associated with one of the two fields.
João G. F. Campos +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
INTERPOLATING STRING FIELD THEORIES [PDF]
Modern Physics Letters A, 1992 A minimal area problem imposing different length conditions on open and closed curves is shown to define a one-parameter family of covariant open-closed quantum string field theories. These interpolate from a recently proposed factorizable open-closed theory up to an extended version of Witten’s open string field theory capable of incorporating on ...
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Homological classification of topological terms in sigma models on homogeneous spaces
Journal of High Energy Physics, 2018 We classify the topological terms (in a sense to be made precise) that may appear in a non-linear sigma model based on maps from an arbitrary worldvolume manifold to a homogeneous space G/H (where G is an arbitrary Lie group and H ⊂ G).
Joe Davighi, Ben Gripaios
doaj +1 more source
SUSY-EXTENDED FIELD THEORY [PDF]
International Journal of Modern Physics A, 2000 A field model on fibre bundles can be extended in a standard way to the BRS-invariant SUSY field model which possesses the Lie supergroup ISp(2) of symmetries.
openaire +3 more sources
Algebraic Coset Conformal field theories
, 2000 All unitary Rational Conformal Field Theories (RCFT) are conjectured to be related to unitary coset Conformal Field Theories, i.e., gauged Wess-Zumino-Witten (WZW) models with compact gauge groups.
Xu, Feng
core +2 more sources
Conformal field theories from deformations of theories with $W_n$ symmetry [PDF]
, 2016 We construct a set of non-rational conformal field theories that consist of deformations of Toda field theory for sl(n). Besides conformal invariance, the theories still enjoy a remnant infinite-dimensional affine symmetry.
Babaro, Juan Pablo +2 more
core +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source