Results 51 to 60 of about 119,004,352 (259)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Modular energy inequalities from relative entropy

Journal of High Energy Physics, 2018
We obtain new constraints for the modular energy of general states by using the monotonicity property of relative entropy. In some cases, modular energy can be related to the energy density of states and these constraints lead to interesting relations ...
David Blanco, Horacio Casini, Mauricio Leston, Felipe Rosso   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

An inverse mass expansion for the mutual information in free scalar QFT at finite temperature

Journal of High Energy Physics, 2020
We study the entanglement entropy and the mutual information in coupled harmonic systems at finite temperature. Interestingly, we find that the mutual information does not vanish at infinite temperature, but it rather reaches a specific finite value ...
Dimitrios Katsinis, Georgios Pastras
doaj   +1 more source

Manifestly SL(2, R) Duality-Symmetric Forms in ModMax Theory

Journal of High Energy Physics, 2022
In this paper, we will investigate a manifestly SL(2, R)-invariant structure for the energy-momentum tensor of ModMax theory as a nonlinear modification of Maxwell electrodynamics which includes conformal invariance as well. In the context of this theory,
H. Babaei-Aghbolagh, Komeil Babaei Velni, Davood Mahdavian Yekta, H. Mohammadzadeh   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Comments on QCD3 and anomalies with fundamental and adjoint matter

Journal of High Energy Physics, 2022
’t Hooft anomaly matching is powerful for constraining the low energy phases of gauge theories. In 3d one common anomaly is the parity anomaly in a T-symmetric theory where one cannot gauge the global symmetry group without breaking the time-reversal ...
Nakarin Lohitsiri, Tin Sulejmanpasic
doaj   +1 more source