Results 111 to 120 of about 11,870,717 (270)

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Field redefinitions and evolutions in relativistic Navier-Stokes

open access: yesJournal of High Energy Physics
In recent years the equations of relativistic first-order viscous hydrodynamics, that is, the relativistic version of Navier-Stokes, have been shown to be well posed and causal under appropriate field redefinitions, also known as hydrodynamic frames.
Yago Bea, Pau Figueras
doaj   +1 more source

Lorentzian bordisms in algebraic quantum field theory [PDF]

open access: yes
It is shown that every algebraic quantum field theory has an underlying functorial field theory which is defined on a suitable globally hyperbolic Lorentzian bordism pseudo-category.
MacManus, James   +2 more
core   +1 more source

Hydrodynamic properties in soliton field theory

open access: yes
The crucial role of hydrodynamic instabilities in soliton field theory is revealed. We demonstrate that the essential of soliton formation mechanism is the sound mode instability induced by thermodynamic instability. This instability triggers phase separation, where new thermal phases are generated to produce solitons. These solitons can be regarded as
openaire   +2 more sources

Dual‐Module Near‐Infrared Fluorophores Discovery System via Knowledge Transfer

open access: yesAdvanced Science, EarlyView.
This study presents a dual‐module deep learning system for the design of near‐infrared (NIR) fluorophores. A large molecular library is generated and analyzed, leading to the suggestions of promising candidates. The effectiveness of the system is further validated through the synthesis, characterization, and in vivo imaging, demonstrating its potential
Yixin Zhu   +7 more
wiley   +1 more source

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia   +9 more
wiley   +1 more source

Relativistic dispersion spectra across Lorentz boosted frames: spurious modes and causality

open access: yesJournal of High Energy Physics
The analysis of excitation spectra in gradient-expanded relativistic fluid theories frequently leads to pathologies under Lorentz boosts. However, extracting the dispersion modes in a Lorentz boosted inertial frame can be nontrivial.
Sayantani Bhattacharyya   +3 more
doaj   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

open access: yesAdvanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin   +8 more
wiley   +1 more source

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