Results 11 to 20 of about 226,046 (275)

Raman Spectroscopic Algorithms for Assessing Virulence in Oral Candidiasis: The Fight-or-Flight Response. [PDF]

Int J Mol Sci
This study aimed to test the effectiveness of Raman spectroscopy in the characterization of the degrees of physiological stress and virulence in clinical swab samples collected from patients affected by oral candidiasis. Raman experiments were conducted on a series of eight isolates, both in an as-collected state and after biofilm purification followed
Pezzotti G, Adachi T, Imamura H, Ikegami S, Kitahara R, Yamamoto T, Kanamura N, Zhu W, Ishibashi KI, Okuma K, Mazda O, Komori A, Komatsuzawa H, Makimura K.   +13 more
europepmc   +4 more sources

Phosphorylation sites required for regulation of cardiac calcium channels in the fight-or-flight response. [PDF]

Proc Natl Acad Sci U S A, 2013
Significance This work defines the in vivo role of phosphorylation of Ser1700 and Thr1704 in Ca V 1.2 channels in the fight-or-flight response. Mutation of both residues to Ala in STAA mice reduced basal L-type Ca 2+ currents and ...
Fu Y, Westenbroek RE, Scheuer T, Catterall WA.   +3 more
europepmc   +4 more sources

The fully activated open state of KCNQ1 controls the cardiac "fight-or-flight" response. [PDF]

PNAS Nexus
AbstractThe cardiac KCNQ1+KCNE1 (IKs) channel regulates heart rhythm in both normal and stress conditions. Under stress, the β-adrenergic stimulation elevates the intracellular cAMP level, leading to KCNQ1 phosphorylation by protein kinase A and increased IKs, which shortens action potentials to adapt to accelerated heart rate.
Hou P, Zhao L, Zhong L, Shi J, Wang HZ, Gao J, Liu H, Zuckerman J, Cohen IS, Cui J.   +9 more
europepmc   +4 more sources

Na/K-ATPase--an integral player in the adrenergic fight-or-flight response. [PDF]

Trends Cardiovasc Med, 2009
During activation of the sympathetic nervous system, cardiac performance is increased as part of the fight-or-flight stress response. The increase in contractility with sympathetic stimulation is an orchestrated combination of intrinsic inotropic, lusitropic, and chronotropic effects, mediated in part by activation of beta-adrenergic receptors and ...
Bers DM, Despa S.
europepmc   +4 more sources

The Odyssey of Dental Anxiety: From Prehistory to the Present. A Narrative Review [PDF]

Frontiers in Psychology, 2017
Dental anxiety (DA) can be considered as a universal phenomenon with a high prevalence worldwide; DA and pain are also the main causes for medical emergencies in the dental office, so their prevention is an essential part of patient safety and overall ...
Enrico Facco, Enrico Facco, Gastone Zanette, Gastone Zanette   +3 more
doaj   +3 more sources

Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice. [PDF]

J Clin Invest, 2010
During the classic "fight-or-flight" stress response, sympathetic nervous system activation leads to catecholamine release, which increases heart rate and contractility, resulting in enhanced cardiac output. Catecholamines bind to β-adrenergic receptors, causing cAMP generation and activation of PKA, which phosphorylates multiple targets in cardiac ...
Shan J, Kushnir A, Betzenhauser MJ, Reiken S, Li J, Lehnart SE, Lindegger N, Mongillo M, Mohler PJ, Marks AR.   +9 more
europepmc   +6 more sources

β-Adrenergic Stimulation Synchronizes a Broad Spectrum of Action Potential Firing Rates of Cardiac Pacemaker Cells toward a Higher Population Average

Cells, 2021
The heartbeat is initiated by pacemaker cells residing in the sinoatrial node (SAN). SAN cells generate spontaneous action potentials (APs), i.e., normal automaticity.
Mary S. Kim, Oliver Monfredi, Larissa A. Maltseva, Edward G. Lakatta, Victor A. Maltsev   +4 more
doaj   +1 more source

Increased Exercise Effort after Artificially-Induced Stress: Laboratory-Based Evidence for the Catharsis Theory of Stress

Baltic Journal of Sport and Health Sciences, 2021
Background. Evolution prepared humans to deal with physical challenges. Today, people encounter psychosocial stress more than physical stress. However, the physiological response to the contemporary forms of stress is still preserved as the biological ...
Attila Szabo, Eliza Tóth, Lili Kósa, Ádám Laki, Ferenc Ihász   +4 more
doaj   +1 more source

Wolf Responses to Experimental Human Approaches Using High-Resolution Positioning Data

Frontiers in Ecology and Evolution, 2022
Humans pose a major mortality risk to wolves. Hence, similar to how prey respond to predators, wolves can be expected to show anti-predator responses to humans. When exposed to a threat, animals may show a fight, flight, freeze or hide response. The type
Erik Versluijs, Ane Eriksen, Boris Fuchs, Camilla Wikenros, Håkan Sand, Petter Wabakken, Barbara Zimmermann   +6 more
doaj   +1 more source

Toxic stress-specific cytoprotective responses regulate learned behavioral decisions in C. elegans

BMC Biology, 2021
Background Recognition of stress and mobilization of adequate “fight-or-flight” responses is key for survival and health. Previous studies have shown that exposure of Caenorhabditis elegans to pathogens or toxins simultaneously stimulates cellular stress
Gábor Hajdú, Eszter Gecse, István Taisz, István Móra, Csaba Sőti   +4 more
doaj   +1 more source