Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Fighting Through Britain. The “Gift Dimension” of Keynes's Quest for a New Global Order [PDF]
Dissatisfied with both Skidelsky's “Fighting for Britain” approach to Keynes's quest for a new global order and its specular competitor, the “Figthing despite Britain” view, we explore the possibility of a “Fighting through Britain” approach to the issue.
Mario A. Cedrini
core
Simulation and Design of an Intelligent Mobile Robot for Fire Fighting [PDF]
The application of traditional frangible glass panel and automatic system such as smoke detector or heat detector requires a human response to realise the existence of fire and to perceive and determine its severity.
Chor, Keong Seng
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Role of Data in Organizing an Access to Justice Movement [PDF]
reminds us that civil justice reform has to start with compelling human stories. She’s right. Building a movement requires drawing in the care and effort of those who previously had not seen the problem.
Gamble, James, Widman, Amy
core +1 more source
Use of Fire-Extinguishing Balls for a Conceptual System of Drone-Assisted Wildfire Fighting
This paper examines the potential use of fire extinguishing balls as part of a proposed system, where drone and remote-sensing technologies are utilized cooperatively as a supplement to traditional firefighting methods. The proposed system consists of (1)
Burchan Aydin +3 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Зарубіжний досвід організації боротьби з шахрайством у страховій системі (Foreign experience of fighting fraud in insurance system) [PDF]
Досліджено зарубіжний досвід організації боротьби з шахрайством у страховій системі. Виокремлено спільні риси та згруповано країни з подібною організацією.
Приказюк, Н. В. (Prykaziuk N. V.)
core
Spread spectrum-based video watermarking algorithms for copyright protection [PDF]
Merged with duplicate record 10026.1/2263 on 14.03.2017 by CS (TIS)Digital technologies know an unprecedented expansion in the last years. The consumer can now benefit from hardware and software which was considered state-of-the-art several years ago ...
Serdean, Cristian Vasile
core +2 more sources

