Results 91 to 100 of about 4,343 (260)

Additional file 7: Figure S7. of HiCPlotter integrates genomic data with interaction matrices

open access: yes, 2015
Example visualization of ChIA-Pet data as arcs with HiCPlotter. a Interaction matrix of mouse embryonic stem cells displayed as a heatmap. b Histograms represent ChIP-Seq assay signals: two tracks are displayed for CTCF and H3K27me3 in mouse embryonic stem cells. c Tile marking the polycomb domain in mouse embryonic stem cells.
Akdemir, Kadir, Chin, Lynda
openaire   +1 more source

Changes in neuropsychological functioning following temporal lobectomy in patients with temporal lobe epilepsy [PDF]

open access: yes, 2009
Purpose: This study was conducted to evaluate the changes in neuropsychological functioning in patients with temporal lobe epilepsy (TLE) after temporal lobe resection.
Chung, C.   +6 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Additional file 9: Figure S9. of HiCPlotter integrates genomic data with interaction matrices

open access: yes, 2015
Cohesin ChIA-PET interactions are enriched in early replication domains. a Density plot represents distribution of Repli-Seq signal for RAD21 ChIA-PET ends (blue), whole genome distribution of Repli-Seq data (red), and randomly selected regions (yellow) in GM12878 cells.
Akdemir, Kadir, Chin, Lynda
openaire   +1 more source

Revisiting the predictive power of thinking styles for academic performance [PDF]

open access: yes, 2004
The present study is a further examination of the contributions of thinking styles to academic achievement (see L-F. Zhang, 2001a, 2001b, 2002f; L-F. Zhang & R. J. Sternberg, 1998).
Zhang, LF
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Additional file 6: Figure S6. of HiCPlotter integrates genomic data with interaction matrices

open access: yes, 2015
Example usage of tiles for presenting tissue-specific enhancer locations with HiCPlotter. a Interaction matrix of mouse embryonic stem cells displayed as a heatmap. b Histograms represent 4C genomic assay signals: two tracks are displayed for Hoxa13 interactions in mouse E12.5 digits (Digits) and in mouse E15.5 genitals (GT).
Akdemir, Kadir, Chin, Lynda
openaire   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Additional file 1: Figure S1. of HiCPlotter integrates genomic data with interaction matrices

open access: yes, 2015
Plotting a whole chromosome with HiCPlotter. Human chromosome 10 as viewed with HiCPlotter. Interaction matrices of GM12878, K562, HUVEC, NHEK, and IMR90 cells are displayed as heatmaps. (PDF 113 kb)
Akdemir, Kadir, Chin, Lynda
openaire   +1 more source

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